Alzheimer's disease (AD) is a public health priority for the 21st century. Risk reduction
currently revolves around lifestyle changes with much research trying to elucidate the …

Background Alzheimer's disease (AD) is the most common cause of dementia in the elderly
and the sixth leading cause of death in the United States. AD is mainly considered a …

Alzheimer's disease (AD)(MIM: 104300) is a highly heritable disease with great complexity
in its genetic contributors, and represents the most common form of dementia. With the …

Alzheimer's disease (AD) is the most common neurodegenerative disease in the world. It is
classified as familial and sporadic. The dominant familial or autosomal presentation …

For two decades the search for genes involved in A lzheimer's disease brought little reward;
it was not until the advent of genome‐wide association studies (GWAS) that genetic …

Highlights•More than 40 loci of interest have been associated with the risk of developing
AD.•Recent genetic data clearly implicate microglia as involved in the pathophysiological …

Introduction Genome‐wide association studies have led to numerous genetic loci
associated with Alzheimer's disease (AD). Whole‐genome sequencing (WGS) now permits …

Alzheimer's disease (AD) is considered to have a large genetic component. Our knowledge
of this component has progressed over the last 10 years, thanks notably to the advent of …

Genome-wide association studies (GWAS) have gained considerable momentum over the
last couple of years for the identification of novel complex disease genes. In the field of …

Alzheimer's disease (AD) is the most common type of dementia and has caused a major
global health concern. Understanding the etiology of AD can be beneficial for the diagnosis …