Evaluation of the Infinium Methylation 450K technology

S Dedeurwaerder, M Defrance, E Calonne, H Denis… - …, 2011 - Taylor & Francis
Aims: Studies of DNA methylomes hold enormous promise for biomedicine but are
hampered by the technological challenges of analyzing many samples cost-effectively …

Complete Pipeline for Infinium® Human Methylation 450K BeadChip Data Processing Using Subset Quantile Normalization for Accurate DNA Methylation Estimation

N Touleimat, J Tost - Epigenomics, 2012 - Taylor & Francis
Background: Huge progress has been made in the development of array-or sequencing-
based technologies for DNA methylation analysis. The Illumina Infinium® Human …

Low-level processing of Illumina Infinium DNA methylation beadarrays

TJ Triche Jr, DJ Weisenberger… - Nucleic acids …, 2013 - academic.oup.com
We propose a novel approach to background correction for Infinium HumanMethylation data
to account for technical variation in background fluorescence signal. Our approach …

Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

MJ Aryee, AE Jaffe, H Corrada-Bravo… - …, 2014 - academic.oup.com
Abstract Motivation: The recently released Infinium HumanMethylation450 array (the
'450k'array) provides a high-throughput assay to quantify DNA methylation (DNAm) at∼ 450 …

Validation of a DNA methylation microarray for 850,000 CpG sites of the human genome enriched in enhancer sequences

S Moran, C Arribas, M Esteller - Epigenomics, 2016 - Taylor & Francis
Aim: DNA methylation is the best known epigenetic mark. Cancer and other pathologies
show an altered DNA methylome. However, delivering complete DNA methylation maps is …

A systematic study of normalization methods for Infinium 450K methylation data using whole-genome bisulfite sequencing data

T Wang, W Guan, J Lin, N Boutaoui, G Canino, J Luo… - Epigenetics, 2015 - Taylor & Francis
DNA methylation plays an important role in disease etiology. The Illumina Infinium
HumanMethylation450 (450K) BeadChip is a widely used platform in large-scale …

[HTML][HTML] A Comparison of the Whole Genome Approach of MeDIP-Seq to the Targeted Approach of the Infinium HumanMethylation450 BeadChip® for Methylome …

C Clark, P Palta, CJ Joyce, C Scott, E Grundberg… - PloS one, 2012 - journals.plos.org
DNA methylation is one of the most studied epigenetic marks in the human genome, with the
result that the desire to map the human methylome has driven the development of several …

Genome-wide DNA methylation analysis of archival formalin-fixed paraffin-embedded tissue using the Illumina Infinium HumanMethylation27 BeadChip

C Thirlwell, M Eymard, A Feber, A Teschendorff… - Methods, 2010 - Elsevier
Aberrant DNA methylation of promoter and other genomic regions can lead to changes in
gene expression, such as over-expression of oncogenes and the silencing of tumour …

Comprehensive characterization, annotation and innovative use of Infinium DNA methylation BeadChip probes

W Zhou, PW Laird, H Shen - Nucleic acids research, 2017 - academic.oup.com
Abstract Illumina Infinium DNA Methylation BeadChips represent the most widely used
genome-scale DNA methylation assays. Existing strategies for masking Infinium probes …

IMA: an R package for high-throughput analysis of Illumina's 450K Infinium methylation data

D Wang, L Yan, Q Hu, LE Sucheston, MJ Higgins… - …, 2012 - academic.oup.com
The Illumina Infinium HumanMethylation450 BeadChip is a newly designed high-density
microarray for quantifying the methylation level of over 450 000 CpG sites within human …