Complement is an evolutionarily conserved system which is important in the defense against
microorganisms and also in the elimination of modified or necrotic elements of the body …

The complement cascade was first recognized as a downstream effector system of antibody-
mediated cytotoxicity. Consistent with this view, it was discovered in the 1960s that …

The complement system functions as a part of the innate immune system. Inappropriate
activation of the complement pathways has a deleterious effect on kidneys. Recent …

The complement system is part of the innate immune response that plays important roles in
protecting the host from foreign pathogens. The complement components and relative …

The complement activation system plays important roles to maintain homeostasis in the host
and to fight foreign invaders to protect the host. Therefore, the complement system is …

It has long been known that the complement cascade is activated in various forms of
glomerulonephritis. In many of these diseases, immune-complexes deposit in the glomeruli …

The complement cascade comprises soluble and cell surface proteins and is an important
arm of the innate immune system. Once activated, the complement system rapidly generates …

Complement is an important component of the innate immune system that is crucial for
defense from microbial infections and for clearance of immune complexes and injured cells …

The complement system plays a key pathogenic role in glomerular diseases with a diverse
range of aetiologies, including C3 glomerulopathy, immunoglobulin A nephropathy …

Abstract The Complement System is an evolutionarily conserved component of immunity
that plays a key role in host defense against infections and tissue homeostasis. However …