Haemolytic uraemic syndrome (HUS) and thrombotic thrombocytopaenic purpura (TTP) are
diseases characterized by microvascular thrombosis, with consequent thrombocytopaenia …

Until recently, atypical hemolytic uremic syndrome (aHUS), conventionally defined in the
pediatric literature as a syndrome of the triad of renal failure, microangiopathic hemolytic …

Thrombotic microangiopathy, which includes thrombotic thrombocytopenic purpura (TTP),
shiga-toxin-associated hemolytic uremic syndrome (Stx-HUS) and atypical HUS, is …

Shiga toxin 1 (Stx-1) and Stx-2 produced by enterohemorrhagic Escherichia coli cause the
diarrhea-associated hemolytic uremic syndrome (HUS). This type of HUS is characterized by …

The complement system contains a great deal of biological “energy”. This is demonstrated
by the atypical hemolytic uremic syndrome (aHUS), which is a thrombotic microangiopathy …

Published data demonstrating the efficacy of complement inhibition therapy in patients with
atypical hemolytic uremic syndrome (aHUS) are remarkable in contrast to the historically …

The 3 major thrombotic microangiopathies (TMAs) are thrombotic thrombocytopenic purpura
(TTP), atypical hemolytic uremic syndrome (aHUS), and Shiga toxin–producing Escherichia …

Complement dysregulation leads to atypical hemolytic uremic syndrome (aHUS), while
ADAMTS13 deficiency causes thrombotic thrombocytopenic purpura. We investigated …

Atypical hemolytic uremic syndrome (aHUS) is characterized by dysregulated complement
activity, the development of a thrombotic microangiopathy (TMA), and widespread end organ …

The haemolytic uraemic syndrome (HUS) includes the triad of haemolytic anaemia,
thrombocytopenia, and acute renal failure. The classical form [D (+) HUS] is caused by …