Over the past decade, zebrafish are being increasingly used in assessing the effects of
chemical compounds. Especially, the embryos and larvae, due to their microscopically small …

The zebrafish model organism is increasingly used for assessing drug toxicity and safety
and numerous studies confirm that mammalian and zebrafish toxicity profiles are strikingly …

Introduction: Over the past decade, zebrafish have been tasked to play important roles from
modeling human diseases to finding cures for them. Inadvertently, these fish now find …

Zebrafish are vertebrate organisms that are of growing interest for preclinical drug discovery
applications. Zebrafish embryos develop most of the major organ systems present in …

Anecdotal evidence has long suggested that zebrafish may be a good model to predict
toxicity of human drugs. As summarized in this review, several groups have recently …

Zebrafish: Methods for Assessing Drug Safety and Toxicity offers a practical guide for using
zebrafish as a tool for toxicology studies. Consolidating key protocols and approaches to …

The zebrafish is increasingly used as a vertebrate animal model for in vivo drug discovery
and for assessing chemical toxicity and safety. Numerous studies have confirmed that …

Traditionally, safety evaluation at the early stage of drug discovery research has been done
using in silico, in vitro, and in vivo systems in this order because of limitations on the amount …

Unpredicted human safety events in clinical trials for new drugs are costly in terms of human
health and money. The drug discovery industry attempts to minimize those events with …

The zebrafish embryo has become an important vertebrate model for assessing drug effects.
It is well suited for studies in genetics, embryology, development, and cell biology. Zebrafish …