Small‐fiber neuropathy: expanding the clinical pain universe
M Sopacua, JGJ Hoeijmakers… - Journal of the …, 2019 - Wiley Online Library
Small‐fiber neuropathy (SFN) is a disorder of thinly myelinated Aδ and unmyelinated C
fibers. SFN is clinically dominated by neuropathic pain and autonomic complaints, leading to …
fibers. SFN is clinically dominated by neuropathic pain and autonomic complaints, leading to …
The clinical approach to small fibre neuropathy and painful channelopathy
Small fibre neuropathy (SFN) is characterised by structural injury selectively affecting small
diameter sensory and/or autonomic axons. The clinical presentation is dominated by pain …
diameter sensory and/or autonomic axons. The clinical presentation is dominated by pain …
Genetic aspects of sodium channelopathy in small fiber neuropathy
JGJ Hoeijmakers, ISJ Merkies, MM Gerrits… - Clinical …, 2012 - Wiley Online Library
Small fiber neuropathy (SFN) is a disorder typically dominated by neuropathic pain and
autonomic dysfunction, in which the thinly myelinated Aδ‐fibers and unmyelinated C‐fibers …
autonomic dysfunction, in which the thinly myelinated Aδ‐fibers and unmyelinated C‐fibers …
Small-fibre neuropathies—advances in diagnosis, pathophysiology and management
JG Hoeijmakers, CG Faber, G Lauria… - Nature Reviews …, 2012 - nature.com
Abstract Small-fibre neuropathy (SFN), a disorder of thinly myelinated Aδ-fibres and
unmyelinated C-fibres, is clinically characterized by neuropathic pain symptoms and …
unmyelinated C-fibres, is clinically characterized by neuropathic pain symptoms and …
Clinical diagnosis and management of small fiber neuropathy: an update on best practice
G Devigili, D Cazzato, G Lauria - Expert review of …, 2020 - Taylor & Francis
Introduction Small fiber neuropathy (SFN) is a heterogeneous group of disorders affecting
thin myelinated Aδ and unmyelinated C fibers. Common symptoms include neuropathic pain …
thin myelinated Aδ and unmyelinated C fibers. Common symptoms include neuropathic pain …
Gain of function NaV1.7 mutations in idiopathic small fiber neuropathy
CG Faber, JGJ Hoeijmakers, HS Ahn… - Annals of …, 2012 - Wiley Online Library
Objective: Small nerve fiber neuropathy (SFN) often occurs without apparent cause, but no
systematic genetic studies have been performed in patients with idiopathic SFN (I‐SFN). We …
systematic genetic studies have been performed in patients with idiopathic SFN (I‐SFN). We …
The G1662S NaV1. 8 mutation in small fibre neuropathy: impaired inactivation underlying DRG neuron hyperexcitability
C Han, D Vasylyev, LJ Macala, MM Gerrits… - Journal of Neurology …, 2014 - jnnp.bmj.com
Objective Painful small fibre neuropathy (SFN) represents a significant public health
problem, with no cause apparent in one-half of cases (termed idiopathic, I-SFN). Gain-of …
problem, with no cause apparent in one-half of cases (termed idiopathic, I-SFN). Gain-of …
Small fiber neuropathy: disease classification beyond pain and burning
TD Levine - Journal of Central Nervous System Disease, 2018 - journals.sagepub.com
Small fiber neuropathy (SFN) has a poorly understood pathology, but patients would benefit
from determination of clinical phenotypes that allows for better diagnosis and treatment …
from determination of clinical phenotypes that allows for better diagnosis and treatment …
Small fiber pathology—a culprit for many painful disorders?
N Üçeyler - Pain, 2016 - journals.lww.com
Small fiber neuropathies (SFNs) are a subgroup of sensory neuropathies that almost
exclusively affect thinly myelinated A-delta or unmyelinated C-nerve fibers. Patients with …
exclusively affect thinly myelinated A-delta or unmyelinated C-nerve fibers. Patients with …
Diagnosing small fiber neuropathy in clinical practice: a deep phenotyping study
N Egenolf, CM Altenschildesche… - Therapeutic …, 2021 - journals.sagepub.com
Background and aims: Small fiber neuropathy (SFN) is increasingly suspected in patients
with pain of uncertain origin, and making the diagnosis remains a challenge lacking a …
with pain of uncertain origin, and making the diagnosis remains a challenge lacking a …