Mouse models for abdominal aortic aneurysm
Abdominal aortic aneurysm (AAA) rupture is estimated to cause 200,000 deaths each year.
Currently, the only treatment for AAA is surgical repair; however, this is only indicated for …
Currently, the only treatment for AAA is surgical repair; however, this is only indicated for …
[HTML][HTML] Experimental models of abdominal aortic aneurysms
JC Tsui - The open cardiovascular medicine journal, 2010 - ncbi.nlm.nih.gov
Despite being a leading cause of death in the West, the pathophysiology of abdominal aortic
aneurysms (AAA) is still incompletely understood. Pharmacotherapy to reduce the growth of …
aneurysms (AAA) is still incompletely understood. Pharmacotherapy to reduce the growth of …
[HTML][HTML] Translating mouse models of abdominal aortic aneurysm to the translational needs of vascular surgery
Introduction Abdominal aortic aneurysm (AAA) is a condition that has considerable
socioeconomic impact and an eventual rupture is associated with high mortality and …
socioeconomic impact and an eventual rupture is associated with high mortality and …
Risk factors and mouse models of abdominal aortic aneurysm rupture
S Murali Krishna, SK Morton, J Li… - International Journal of …, 2020 - mdpi.com
Abdominal aortic aneurysm (AAA) rupture is an important cause of death in older adults. In
clinical practice, the most established predictor of AAA rupture is maximum AAA diameter …
clinical practice, the most established predictor of AAA rupture is maximum AAA diameter …
Translational relevance and recent advances of animal models of abdominal aortic aneurysm
J Sénémaud, G Caligiuri, H Etienne… - … , and vascular biology, 2017 - Am Heart Assoc
Human abdominal aortic aneurysm (AAA) pathophysiology is not yet completely understood.
In conductance arteries, the insoluble extracellular matrix, synthesized by vascular smooth …
In conductance arteries, the insoluble extracellular matrix, synthesized by vascular smooth …
The pathophysiologic basis of abdominal aortic aneurysm progression: a critical appraisal
JHN Lindeman - Expert review of cardiovascular therapy, 2015 - Taylor & Francis
An aneurysm of the abdominal aorta is a common pathology and a major cause of sudden
death in the elderly. Currently, abdominal aortic aneurysms (AAAs) can only be treated by …
death in the elderly. Currently, abdominal aortic aneurysms (AAAs) can only be treated by …
Animal models of abdominal aortic aneurysm and their role in furthering management of human disease
Abdominal aortic aneurysm is a common degenerative disorder associated with sudden
death due to aortic rupture. Current therapy is limited to open surgical repair of the aorta or …
death due to aortic rupture. Current therapy is limited to open surgical repair of the aorta or …
Mouse models of abdominal aortic aneurysms
A Daugherty, LA Cassis - Arteriosclerosis, thrombosis, and …, 2004 - Am Heart Assoc
Many mouse models of abdominal aortic aneurysms have been developed that use a
diverse array of methods for producing the disease, including genetic manipulation and …
diverse array of methods for producing the disease, including genetic manipulation and …
Abdominal aortic aneurysms: fresh insights from a novel animal model of the disease
MW Manning, LA Cassis, J Huang… - Vascular …, 2002 - journals.sagepub.com
Abdominal aortic aneurysms (AAA) have a high prevalence in aged populations and are
responsible for a large number of deaths. Despite the widespread nature of the disease …
responsible for a large number of deaths. Despite the widespread nature of the disease …
[HTML][HTML] Animal models used to explore abdominal aortic aneurysms: a systematic review
JL Poulsen, J Stubbe, JS Lindholt - European Journal of Vascular and …, 2016 - Elsevier
Objective Experimental animal models have been used to investigate the formation,
development, and progression of abdominal aortic aneurysms (AAAs) for decades. New …
development, and progression of abdominal aortic aneurysms (AAAs) for decades. New …