Studying fungal pathogens of humans and fungal infections: Fungal diversity and diversity of approaches

G Janbon, J Quintin, F Lanternier, C d'Enfert - Microbes and Infection, 2019 - Elsevier
Abstract Seminal work by Louis Pasteur revealed the contribution of fungi–yeasts and
microsporidia to agroindustry and disease in animals, respectively. More than 150 years …

Hidden killers: human fungal infections

GD Brown, DW Denning, NAR Gow, SM Levitz… - Science translational …, 2012 - science.org
Although fungal infections contribute substantially to human morbidity and mortality, the
impact of these diseases on human health is not widely appreciated. Moreover, despite the …

Emergence and evolution of virulence in human pathogenic fungi

S Siscar-Lewin, B Hube, S Brunke - Trends in microbiology, 2022 - cell.com
One billion people worldwide are affected by fungal pathogens, of which 1.6 million
succumb to fungal infections per year. This review discusses the emergence and evolution …

Comparative genomics allowed the identification of drug targets against human fungal pathogens

AKR Abadio, ES Kioshima, MM Teixeira, NF Martins… - BMC genomics, 2011 - Springer
Background The prevalence of invasive fungal infections (IFIs) has increased steadily
worldwide in the last few decades. Particularly, there has been a global rise in the number of …

Virulence factors in fungal pathogens of man

S Brunke, S Mogavero, L Kasper, B Hube - Current opinion in microbiology, 2016 - Elsevier
Highlights•Fungi are often neglected, important human pathogens.•Survival and growth in
the host are prerequisites for pathogenesis.•Host damage derives from an interplay between …

Using non-mammalian hosts to study fungal virulence and host defense

BB Fuchs, E Mylonakis - Current opinion in microbiology, 2006 - Elsevier
Non-mammalian hosts have been used to study host–fungal interactions. Hosts such as
Drosophila melanogaster, Caenorhabditis elegans, Acathamoeba castellanii, Dictyostelium …

Genetic susceptibility to fungal infections and links to human ancestry

B Naik, SMQ Ahmed, S Laha, SP Das - Frontiers in genetics, 2021 - frontiersin.org
Over the ages, fungi have associated with different parts of the human body and established
symbiotic associations with their host. They are mostly commensal unless there are certain …

Medically important bacterial–fungal interactions

AY Peleg, DA Hogan, E Mylonakis - Nature reviews microbiology, 2010 - nature.com
Whether it is in the setting of disease or in a healthy state, the human body contains a
diverse range of microorganisms, including bacteria and fungi. The interactions between …

A global view on fungal infections in humans and animals: opportunistic infections and microsporidioses

S Gnat, D Łagowski, A Nowakiewicz… - Journal of Applied …, 2021 - academic.oup.com
After cardiovascular diseases, infectious diseases are the second most common cause of
death worldwide. Although these infections are caused mainly by viruses or bacteria, a …

Immunity to fungal infections

L Romani - Nature Reviews Immunology, 2011 - nature.com
Fungal diseases represent an important paradigm in immunology, as they can result from
either a lack of recognition by the immune system or overactivation of the inflammatory …