The new insights into autophagy in thyroid cancer progression

YB Shi, SY Chen, RB Liu - Journal of Translational Medicine, 2023 - Springer
In recent decades, the incidence of thyroid cancer keeps growing at a shocking rate, which
has aroused increasing concerns worldwide. Autophagy is a fundamental and ubiquitous …

Autophagy in thyroid cancer: present knowledge and future perspectives

RT Netea-Maier, V Klück, TS Plantinga… - Frontiers in …, 2015 - frontiersin.org
Thyroid cancer is the most common endocrine malignancy. Despite having a good
prognosis in the majority of cases, when the tumor is dedifferentiated it does no longer …

Autophagy: A potential target for thyroid cancer therapy

H Yi, B Long, X Ye, L Zhang… - Molecular and …, 2014 - spandidos-publications.com
The sharply increasing incidence of thyroid cancer has attracted considerable attention over
the last few years. The combination of surgery, radioiodine ablation and thyroid‑stimulating …

Targeting autophagy in thyroid cancer: EMT, apoptosis, and cancer stem cells

TM Holm, S Yeo, KM Turner, JL Guan - Frontiers in Cell and …, 2022 - frontiersin.org
Autophagy is a highly conserved recycling process through which cellular homeostasis is
achieved and maintained. With respect to cancer biology, autophagy acts as a double …

Targeting autophagy in thyroid cancers

W Wei, H Hardin, QY Luo - Endocrine-related cancer, 2019 - erc.bioscientifica.com
Thyroid cancer is one of the most common endocrine malignancies. Although the prognosis
for the majority of thyroid cancers is relatively good, patients with metastatic, radioiodine …

Autophagy, a novel target for chemotherapeutic intervention of thyroid cancer

L Li, G Liu, X Zhang, Y Li - Cancer chemotherapy and pharmacology, 2014 - Springer
Purpose Thyroid cancers with unsatisfactory curative effect nowadays are the most common
malignant tumors of the endocrine system. Apoptosis evasion, a hallmark of cancer, has …

Inhibition of autophagy mitigates cell migration and invasion in thyroid cancer

TM Holm, ZC Bian, K Manupati, JL Guan - Surgery, 2022 - Elsevier
Background Autophagy is a highly conserved process for maintaining cellular homeostasis.
Upregulation of autophagy promotes metastasis by promoting the cancer stem cell state …

[HTML][HTML] Comprehensive analysis of the clinical significance and prospective molecular mechanisms of differentially expressed autophagy-related genes in thyroid …

P Lin, Y He, DY Wen, XJ Li… - International …, 2018 - spandidos-publications.com
Thyroid cancer (TC) is the most common endocrine malignancy, accounting for
approximately 90% of all malignancies of the endocrine system. Despite the fact that …

[PDF][PDF] Autophagy in endocrine tumors

A Weckman, F Rotondo, A Di Ieva, LV Syro… - Endocr Relat …, 2015 - researchgate.net
Autophagy is an important intracellular process involving the degradation of cytoplasmic
components. It is involved in both physiological and pathological conditions, including …

Autophagy: a new target for advanced papillary thyroid cancer therapy

CI Lin, EE Whang, MA Abramson, X Jiang, BD Price… - Surgery, 2009 - Elsevier
BACKGROUND: Autophagy is a conserved response to stress that facilitates cell survival in
some contexts and promotes cell death in others. We sought to characterize autophagy in …