BACKGROUND: Cerebral aneurysms (CAs) have a high prevalence in the general
population and cause lethal subarachnoid hemorrhage. We recently demonstrated that …

Cerebral aneurysm (CA) causes catastrophic subarachnoid hemorrhage which is
characterized by a high mortality and morbidity rate. CA is a common disease worldwide but …

OBJECTIVE: Recent investigations strongly suggest that the pathophysiology of cerebral
aneurysms (CA) is closely associated with chronic inflammation in vascular walls. Nuclear …

Angiotensin-(1-7)(Ang-(1-7)) can regulate vascular inflammation and remodeling, which are
processes that have important roles in the pathophysiology of intracranial aneurysms. In this …

The formation, growth, and rupture of intracranial aneurysms (IAs) involve hemodynamics,
blood pressure, external stimuli, and a series of hormonal changes. In addition, inflammatory …

Object Although cerebral aneurysmal subarachnoid hemorrhage is a devastating disease
for humans, effective medical treatments have not yet been established. Recent reports have …

Background and Purpose—Subarachnoid hemorrhage caused by cerebral aneurysm
rupture remains a life-threatening emergency despite advances in treatment. However, the …

Subarachnoid hemorrhage (SAH) is mainly attributable to the rupture of intracranial
aneurysms (IAs). Although the outcome of SAH is considerably poor in spite of the recent …

Abnormal vascular remodeling mediated by inflammatory cells has been identified as a key
pathologic component of various vascular diseases, including abdominal aortic aneurysms …

The treatment of cerebral aneurysms (CAs) is of social importance, because poor outcomes
result in subarachnoid hemorrhages after rupture. However, there is currently no medical …