Impairment of sperm DNA methylation in male infertility: a meta‐analytic study
D Santi, S De Vincentis, E Magnani, G Spaggiari - Andrology, 2017 - Wiley Online Library
Considering the widespread use of assisted reproductive techniques (ART), DNA
methylation of specific genes involved in spermatogenesis achieves increasingly clinical …
methylation of specific genes involved in spermatogenesis achieves increasingly clinical …
DNA methylation in human sperm: a systematic review
BACKGROUND Studies in non-human mammals suggest that environmental factors can
influence spermatozoal DNA methylation, and some research suggests that spermatozoal …
influence spermatozoal DNA methylation, and some research suggests that spermatozoal …
[HTML][HTML] DNA methylation in spermatogenesis and male infertility
X Cui, X Jing, X Wu, M Yan, Q Li… - Experimental and …, 2016 - spandidos-publications.com
Infertility is a significant problem for human reproduction, with males and females equally
affected. However, the molecular mechanisms underlying male infertility remain unclear …
affected. However, the molecular mechanisms underlying male infertility remain unclear …
Sperm global DNA methylation level: association with semen parameters and genome integrity
D Montjean, A Zini, C Ravel, S Belloc, A Dalleac… - …, 2015 - Wiley Online Library
Sperm DNA methylation abnormalities have been detected in oligozoospermic men.
However, the association between sperm DNA methylation defects, sperm parameters and …
However, the association between sperm DNA methylation defects, sperm parameters and …
Aberrant DNA methylation patterns of spermatozoa in men with unexplained infertility
RG Urdinguio, GF Bayon, M Dmitrijeva… - Human …, 2015 - academic.oup.com
Abstract STUDY QUESTION Are there DNA methylation alterations in sperm that could
explain the reduced biological fertility of male partners from couples with unexplained …
explain the reduced biological fertility of male partners from couples with unexplained …
[HTML][HTML] Genome-wide sperm deoxyribonucleic acid methylation is altered in some men with abnormal chromatin packaging or poor in vitro fertilization embryogenesis
OBJECTIVE: To evaluate genome-wide DNA methylation patterns in sperm from men with
abnormal sperm chromatin packaging and patients displaying abnormal embryogenesis …
abnormal sperm chromatin packaging and patients displaying abnormal embryogenesis …
[HTML][HTML] Alterations in sperm DNA methylation patterns at imprinted loci in two classes of infertility
OBJECTIVE: To evaluate the associations between proper protamine incorporation and
DNA methylation at imprinted loci. DESIGN: Experimental research study. SETTING …
DNA methylation at imprinted loci. DESIGN: Experimental research study. SETTING …
[HTML][HTML] Decreased fecundity and sperm DNA methylation patterns
Objective To evaluate the relationship between epigenetic patterns in sperm and fecundity.
Design Prospective study. Setting Academic andrology and in vitro fertilization laboratory …
Design Prospective study. Setting Academic andrology and in vitro fertilization laboratory …
[HTML][HTML] Aberrant sperm DNA methylation predicts male fertility status and embryo quality
Objective To evaluate whether male fertility status and/or embryo quality during in vitro
fertilization (IVF) therapy can be predicted based on genomewide sperm deoxyribonucleic …
fertilization (IVF) therapy can be predicted based on genomewide sperm deoxyribonucleic …
[HTML][HTML] Epigenetics of male infertility: the role of DNA methylation
JC Rotondo, C Lanzillotti, C Mazziotta… - Frontiers in Cell and …, 2021 - frontiersin.org
In recent years, a number of studies focused on the role of epigenetics, including DNA
methylation, in spermatogenesis and male infertility. We aimed to provide an overview of the …
methylation, in spermatogenesis and male infertility. We aimed to provide an overview of the …