DNA methylation is critical for the normal development and functioning of the human brain,
such as the proliferation and differentiation of neural stem cells, synaptic plasticity, neuronal …

Simple Summary DNA methylation is an epigenetic modification of genes which affects
corresponding gene expression. During the developmental stage, embryonic stem cells …

Genome-wide studies related to neurological disorders and neurodegenerative diseases
have pointed to the role of epigenetic changes such as DNA methylation, histone …

DNA methylation at CpG sites is an essential epigenetic mark that regulates gene
expression during mammalian development and diseases. Methylome refers to the entire …

ABSTRACT DNA methylation, which has been investigated extensively recently, has been
studied in various human diseases, including cancer, and the analysis of DNA methylation …

Simple Summary DNA methylation is involved in biological processes including
neurogenesis, aging, and the pathogenesis of brain disorders by the regulation of gene …

DNA methylation is a broadly-investigated epigenetic modification that has been considered
as a heritable and reversible change. Previous findings have indicated that DNA methylation …

Epigenetic alterations represent a sort of functional modifications related to the genome that
are not responsible for changes in the nucleotide sequence. DNA methylation is one of such …

DNA methylation is a class of epigenetic modification essential for coordinating gene
expression timing and magnitude throughout normal brain development and for proper brain …

Over the last decade, an increasing number of reports underscored the importance of
epigenetic regulations in brain plasticity. Epigenetic elements such as readers, writers and …