[HTML][HTML] The DNA methylation in neurological diseases

S Younesian, AM Yousefi, M Momeny, SH Ghaffari… - Cells, 2022 - mdpi.com
DNA methylation is critical for the normal development and functioning of the human brain,
such as the proliferation and differentiation of neural stem cells, synaptic plasticity, neuronal …

[HTML][HTML] DNA methylation: a promising approach in management of Alzheimer's disease and other neurodegenerative disorders

G Kaur, SSS Rathod, MM Ghoneim, S Alshehri… - Biology, 2022 - mdpi.com
Simple Summary DNA methylation is an epigenetic modification of genes which affects
corresponding gene expression. During the developmental stage, embryonic stem cells …

[HTML][HTML] The role of DNA methylation in progression of neurological disorders and neurodegenerative diseases as well as the prospect of using DNA methylation …

Y Rasmi, A Shokati, A Hassan, SGG Aziz… - IBRO Neuroscience …, 2023 - Elsevier
Genome-wide studies related to neurological disorders and neurodegenerative diseases
have pointed to the role of epigenetic changes such as DNA methylation, histone …

[HTML][HTML] A concise review of human brain methylome during aging and neurodegenerative diseases

GR Prasad, E Jho - BMB reports, 2019 - ncbi.nlm.nih.gov
DNA methylation at CpG sites is an essential epigenetic mark that regulates gene
expression during mammalian development and diseases. Methylome refers to the entire …

DNA methylation as a biomarker for neuropsychiatric diseases

S Ai, L Shen, J Guo, X Feng, B Tang - International Journal of …, 2012 - Taylor & Francis
ABSTRACT DNA methylation, which has been investigated extensively recently, has been
studied in various human diseases, including cancer, and the analysis of DNA methylation …

[HTML][HTML] Dynamic regulation of DNA methylation and brain functions

J Xie, L Xie, H Wei, XJ Li, L Lin - Biology, 2023 - mdpi.com
Simple Summary DNA methylation is involved in biological processes including
neurogenesis, aging, and the pathogenesis of brain disorders by the regulation of gene …

DNA methylation signature as a biomarker of major neuropsychiatric disorders

Z Shirvani-Farsani, Z Maloum… - Journal of Psychiatric …, 2021 - Elsevier
DNA methylation is a broadly-investigated epigenetic modification that has been considered
as a heritable and reversible change. Previous findings have indicated that DNA methylation …

[HTML][HTML] DNA methylation, a hand behind neurodegenerative diseases

H Lu, X Liu, Y Deng, H Qing - Frontiers in aging neuroscience, 2013 - frontiersin.org
Epigenetic alterations represent a sort of functional modifications related to the genome that
are not responsible for changes in the nucleotide sequence. DNA methylation is one of such …

Diverse and dynamic DNA modifications in brain and diseases

MJ Armstrong, Y Jin, EG Allen… - Human molecular …, 2019 - academic.oup.com
DNA methylation is a class of epigenetic modification essential for coordinating gene
expression timing and magnitude throughout normal brain development and for proper brain …

[HTML][HTML] The role of activity-dependent DNA demethylation in the adult brain and in neurological disorders

G Bayraktar, MR Kreutz - Frontiers in molecular neuroscience, 2018 - frontiersin.org
Over the last decade, an increasing number of reports underscored the importance of
epigenetic regulations in brain plasticity. Epigenetic elements such as readers, writers and …