Methionine adenosyltransferase 1A knockout mice are predisposed to liver injury and exhibit increased expression of genes involved in proliferation
SC Lu, L Alvarez, ZZ Huang, L Chen… - Proceedings of the …, 2001 - National Acad Sciences
Liver-specific and nonliver-specific methionine adenosyltransferases (MATs) are products of
two genes, MAT1A and MAT2A, respectively, that catalyze the formation of S …
two genes, MAT1A and MAT2A, respectively, that catalyze the formation of S …
S-adenosylmethionine regulates MAT1A and MAT2A gene expression in cultured rat hepatocytes: a new role for S-adenosylmethionine in the maintenance of the …
E Ruiz Garcia-Trevijano, MU Latasa, M Carretero… - 2000 - dadun.unav.edu
Methionine metabolism starts with the formation of S-adenosylmethionine (AdoMet), the
most important biological methyl donor. This reaction is catalyzed by methionine …
most important biological methyl donor. This reaction is catalyzed by methionine …
Liver-specific methionine adenosyltransferase MAT1A gene expression is associated with a specific pattern of promoter methylation and histone acetylation …
L Torres, MA Avila, M Carretero, MU Latasa… - 2000 - dadun.unav.edu
Methionine adenosyltransferase (MAT) is the enzyme that catalyzes the synthesis of S-
adenosylmethionine (AdoMet), the main donor of methyl groups in the cell. In mammals MAT …
adenosylmethionine (AdoMet), the main donor of methyl groups in the cell. In mammals MAT …
Changes in methionine adenosyltransferase during liver regeneration in the rat
ZZ Huang, Z Mao, J Cai, SC Lu - American Journal of …, 1998 - journals.physiology.org
Liver-specific and non-liver-specific methionine adenosyltransferase (MAT) are products of
two genes (MAT1A and MAT2A, respectively) that catalyze the formation of S …
two genes (MAT1A and MAT2A, respectively) that catalyze the formation of S …
S-Adenosylmethionine: a control switch that regulates liver function
JM Mato, FJ Corrales, SC Lu, MA Avila - 2002 - dadun.unav.edu
Genome sequence analysis reveals that all organisms synthesize S-adenosylmethionine
(AdoMet) and that a large fraction of all genes is AdoMet-dependent methyltransferases …
(AdoMet) and that a large fraction of all genes is AdoMet-dependent methyltransferases …
L-methionine availability regulates expression of the methionine adenosyltransferase 2A gene in human hepatocarcinoma cells: role of S-adenosylmethionine
ML Martínez-Chantar, MU Latasa, M Varela-Rey… - Journal of Biological …, 2003 - ASBMB
In mammals, methionine adenosyltransferase (MAT), the enzyme responsible for S-
adenosylmethionine (AdoMet) synthesis, is encoded by two genes, MAT1A and MAT2A. In …
adenosylmethionine (AdoMet) synthesis, is encoded by two genes, MAT1A and MAT2A. In …
Impaired liver regeneration in mice lacking methionine adenosyltransferase 1A
L Chen, Y Zeng, H Yang, TD Lee, SW French… - The FASEB …, 2004 - Wiley Online Library
Methionine adenosyltransferase (MAT) is an essential enzyme because it catalyzes the
formation of S‐adenosylmethionine (SAMe), the principal biological methyl donor. Of the two …
formation of S‐adenosylmethionine (SAMe), the principal biological methyl donor. Of the two …
Changes in methionine adenosyltransferase and S-adenosylmethionine homeostasis in alcoholic rat liver
Liver-specific and non-liver-specific methionine adenosyltransferase (MAT) are products of
two genes, MAT1A and MAT2A, respectively, that catalyze the formation of S …
two genes, MAT1A and MAT2A, respectively, that catalyze the formation of S …
S‐Adenosylmethionine in cell growth, apoptosis and liver cancer
SC Lu, JM Mato - Journal of gastroenterology and hepatology, 2008 - Wiley Online Library
Abstract S‐Adenosylmethionine (SAMe), the principal biological methyl donor, is
synthesized from methionine and ATP in a reaction catalyzed by methionine …
synthesized from methionine and ATP in a reaction catalyzed by methionine …
Differential expression of methionine adenosyltransferase genes influences the rate of growth of human hepatocellular carcinoma cells
J Cai, Z Mao, JJ Hwang, SC Lu - Cancer research, 1998 - AACR
Methionine adenosyltransferase (MAT) catalyzes the formation of S-adenosylmethionine
(SAM), the principal methyl donor, and is essential to normal cell function. The two forms of …
(SAM), the principal methyl donor, and is essential to normal cell function. The two forms of …