Abstract Collagen alpha-1 (III) chain, also known as the alpha 1 chain of type III collagen, is
a protein that in humans is encoded by the COL3A1 gene. Three alpha 1 chains are …

Type III collagen is a fibrillar forming collagen comprising three α1 (III) chains and is
expressed in early embryos and throughout embryogenesis. In the adult, type III collagen is …

Type III collagen is a major fibrillar collagen consisting of three identical α 1 (III)-chains that
is particularly present in tissues exhibiting elastic properties, such as the skin and the arterial …

Mutations in the COL3A1 gene that encodes the chains of type III procollagen result in the
vascular form of Ehlers-Danlos syndrome (EDS), EDS type IV, if they alter the sequence in …

Abstract The Ehlers-Danlos syndrome (EDS) is a heterogeneous connective-tissue disorder
of which at least nine subtypes are recognized. Considerable clinical overlap exists between …

We have identified haploinsufficiency of the COL5A1 gene that encodes the proα1 (V) chain
of type V collagen in the classical form of the Ehlers-Danlos syndrome (EDS), a heritable …

Type V collagen is a constituent of type I collagen-rich fibrils in many connective tissues and
is a regulator of fibril diameter. In tissues, type V collagen is a heterotrimer with the …

Ehlers-Danlos syndrome (EDS) is a heterogeneous group of connective tissue disorders.
Recently mutations have been found in the genes for type V collagen in a small number of …

Abstract Type III collagen (Col3), a fibril-forming collagen, is a major extracellular matrix
component in a variety of internal organs and skin. It is also expressed at high levels during …

Type II collagen, comprised of three identical alpha-1 (II) chains, is the major collagen
synthesized by chondrocytes, and is found in articular cartilage, vitreous humour, inner ear …