The incidence rate and histological characteristics of intimal hyperplasia in elastase‐induced experimental abdominal aortic aneurysms in mice
M Li, P Wei, K Li, H Liu, N Alam, H Hou… - Animal Models and …, 2023 - Wiley Online Library
Intimal hyperplasia (IH) is a negative vascular remodeling after arterial injury. IH
occasionally occurs in elastase‐induced abdominal aortic aneurysm (AAA) mouse models …
occasionally occurs in elastase‐induced abdominal aortic aneurysm (AAA) mouse models …
Extra-and intraluminal elastase induce morphologically distinct abdominal aortic aneurysms in mice and thus represent specific subtypes of human disease
Topical application of elastase to induce arterial aneurysm formation is an emerging murine
model of vascular disease. In the context of aortic abdominal aneurysm (AAA), angiotensin II …
model of vascular disease. In the context of aortic abdominal aneurysm (AAA), angiotensin II …
Experimental aortic aneurysm severity and growth depend on topical elastase concentration and lysyl oxidase inhibition
Abdominal aortic aneurysm (AAA) formation and expansion is highly complex and
multifactorial, and the improvement of animal models is an important step to enhance our …
multifactorial, and the improvement of animal models is an important step to enhance our …
Differential gender-and species-specific formation of aneurysms using a novel method of inducing abdominal aortic aneurysms
A Laser, G Lu, A Ghosh, K Roelofs, B McEvoy… - journal of surgical …, 2012 - Elsevier
BACKGROUND: The objective of this study was to test a novel model of inducing abdominal
aortic aneurysms (AAAs) in different mouse strains and genders. MATERIALS AND …
aortic aneurysms (AAAs) in different mouse strains and genders. MATERIALS AND …
Temporal and Quantitative Analysis of Aortic Immunopathologies in Elastase‐Induced Mouse Abdominal Aortic Aneurysms
K Tian, C Xia, H Liu, B Xu, P Wei, W Fu… - Journal of …, 2021 - Wiley Online Library
Objective. Elastase‐induced abdominal aortic aneurysm (AAA) model is widely used for
aneurysmal pathogenesis and translational research. However, temporal alternations in …
aneurysmal pathogenesis and translational research. However, temporal alternations in …
[HTML][HTML] Hyperlipidemia does not affect development of elastase-induced abdominal aortic aneurysm in mice
J Mulorz, JM Spin, HC Beck, MLT Thi… - Atherosclerosis, 2020 - Elsevier
Background and aims Hyperlipidemia is a suggested risk factor for abdominal aortic
aneurysm (AAA). However, whether hyperlipidemia is causally involved in AAA progression …
aneurysm (AAA). However, whether hyperlipidemia is causally involved in AAA progression …
[HTML][HTML] In vivo assessment of murine elastase-induced abdominal aortic aneurysm with high resolution magnetic resonance imaging
MA Bartoli, F Kober, P Cozzone, RW Thompson… - European Journal of …, 2012 - Elsevier
OBJECTIVES: There are, to date, no published non-invasive or longitudinal studies
performed in mice to measure aortic diameter and wall thickness in an elastase-induced …
performed in mice to measure aortic diameter and wall thickness in an elastase-induced …
Indomethacin prevents elastase-induced abdominal aortic aneurysms in the rat
DR Holmes, D Petrinec, W Wester… - Journal of Surgical …, 1996 - Elsevier
Perfusion of the rat abdominal aorta with elastase induces abdominal aortic aneurysms
(AAA), in which the development of aortic dilatation correlates with the influx of inflammatory …
(AAA), in which the development of aortic dilatation correlates with the influx of inflammatory …
[HTML][HTML] Temporal changes in mouse aortic wall gene expression during the development of elastase-induced abdominal aortic aneurysms
SJ Van Vickle-Chavez, WS Tung, TS Absi… - Journal of vascular …, 2006 - Elsevier
OBJECTIVE: To characterize temporal changes in mouse aortic wall gene expression
associated with the development of experimental abdominal aortic aneurysms. METHODS …
associated with the development of experimental abdominal aortic aneurysms. METHODS …
Degeneration and Regeneration of Smooth Muscle Cells in Two Different Abdominal Aortic Aneurysm Models in Rabbits
Y Bi, J Guo, M Yi, Y Gao, J Ren, X Han - Annals of Vascular Surgery, 2022 - Elsevier
Background We aimed to investigate the formation and self-healing process of rabbit
abdominal aortic aneurysm (AAA) by focus on the degeneration and regeneration of smooth …
abdominal aortic aneurysm (AAA) by focus on the degeneration and regeneration of smooth …