Neuroblastoma (NB) is a neoplasm of the sympathetic nervous system, and is the most
common solid tumor of infancy. NBs are very heterogeneous, with a clinical course ranging …

Glioblastoma (GBM) is the most aggressive tumors of the central nervous system. Here, we
report that SH3 binding glutamic acid-rich protein like 3 (SH3BGRL3) was extremely highly …

Background Glioblastoma (GBM) is a prevalent brain malignancy with an extremely poor
prognosis, which is attributable to its invasive biological behavior. The RNA-binding motif …

Glioblastoma multiforme (GBM) is an aggressive malignant brain tumour that is resistant to
existing therapeutics. Identifying signalling pathways deregulated in GBM that can be …

Hepatocellular carcinoma (HCC) is the most common form of liver cancer and is typically
diagnosed at advanced stages. Identification and characterisation of genes within amplified …

Abstract Background Glioma stem cells (GSCs) are considered the initial cells of gliomas,
contributing to therapeutic resistance. Patient-derived GSCs well recapitulate the …

Atypical teratoid rhabdoid tumors (ATRTs) are challenging pediatric brain cancers that are
predominantly associated with inactivation of the gene SMARCB1, a conserved subunit of …

Diffuse midline gliomas are uniformly fatal pediatric central nervous system cancers that are
refractory to standard-of-care therapeutic modalities. The primary genetic drivers are a set of …

Abstract SMARCB1 (Snf5/Ini1/Baf47) is a potent tumor suppressor, the loss of which serves
as the diagnostic feature in malignant rhabdoid tumors (MRT) and atypical teratoid/rhabdoid …

Neuroblastoma (NB) is an embryonic malignancy of the sympathetic nervous system with
heterogeneous biological, morphological, genetic and clinical characteristics. Although …