Treatment of neonatal seizures: comparison of treatment pathways from 11 neonatal intensive care units

JC Keene, LA Morgan, NS Abend, SV Bates… - Pediatric …, 2022 - Elsevier
Objective Seizures are a common neonatal neurologic emergency. Many centers have
developed pathways to optimize management. We evaluated neonatal seizure management …

Neonatal seizures: treatment and treatment variability in 31 United States pediatric hospitals

HK Blume, MM Garrison… - Journal of child …, 2009 - journals.sagepub.com
Neonatal seizures are one of the most common neurological disorders in infants. However,
the optimal treatment strategy for neonatal seizures remains controversial and there is little …

Neonatal seizures: multicenter variability in current treatment practices

AI Bartha, J Shen, KH Katz, RE Mischel, KR Yap… - Pediatric …, 2007 - Elsevier
Standardized approaches to the treatment of neonatal seizures remain undeveloped. We
assessed the type and number of anticonvulsants selected, blood levels attained, and …

Contemporary profile of seizures in neonates: a prospective cohort study

HC Glass, RA Shellhaas, CJ Wusthoff, T Chang… - The Journal of …, 2016 - Elsevier
Objective To determine the contemporary etiology, burden, and short-term outcomes of
seizures in neonates monitored with continuous video-electroencephalogram (cEEG). Study …

Off-label use of antiepileptic drugs for the treatment of neonatal seizures

FS Silverstein, DM Ferriero - Pediatric neurology, 2008 - Elsevier
Medically refractory neonatal seizures represent a major therapeutic challenge in neonatal
intensive care units. Conventional antiepileptic drugs demonstrate limited efficacy. Previous …

Seizure classification, etiology, and management

RA Shellhaas - Handbook of clinical neurology, 2019 - Elsevier
The first weeks of life are a time of heightened risk for seizures due to age-dependent
physiologic features of the developing brain that lead to increased neuronal excitation and …

Treatment of seizures in the neonate: Guidelines and consensus‐based recommendations—Special report from the ILAE Task Force on Neonatal Seizures

RM Pressler, NS Abend, S Auvin, G Boylan, F Brigo… - …, 2023 - Wiley Online Library
Seizures are common in neonates, but there is substantial management variability. The
Neonatal Task Force of the International League Against Epilepsy (ILAE) developed …

Acute symptomatic seizures in neonates

HC Glass, RA Shellhaas - Seminars in Pediatric Neurology, 2019 - Elsevier
Seizures are an important sign of neurologic dysfunction in neonates, and they most often
represent acute brain injury such as hypoxic-ischemic encephalopathy, stroke, or …

[HTML][HTML] Neonatal seizure management: is the timing of treatment critical?

AM Pavel, JM Rennie, LS de Vries, M Blennow… - The Journal of …, 2022 - Elsevier
Objective To assess the impact of the time to treatment of the first electrographic seizure on
subsequent seizure burden and describe overall seizure management in a large neonatal …

Pharmacological treatment of neonatal seizures: a systematic review

LA Slaughter, AD Patel… - Journal of child …, 2013 - journals.sagepub.com
Pharmacologic treatment options for neonatal seizures have expanded over the past 2
decades, and there is no consensus on optimal treatment strategy. We systematically …