Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase
Gene silencing in eukaryotes is associated with the formation of heterochromatin, a complex
of proteins and DNA that block transcription. Heterochromatin is characterized by the …
of proteins and DNA that block transcription. Heterochromatin is characterized by the …
Trimethylated lysine 9 of histone H3 is a mark for DNA methylation in Neurospora crassa
H Tamaru, X Zhang, D McMillen, PB Singh… - Nature …, 2003 - nature.com
Besides serving to package nuclear DNA, histones carry information in the form of a diverse
array of post-translational modifications. Methylation of histones H3 and H4 has been …
array of post-translational modifications. Methylation of histones H3 and H4 has been …
Interplay between two epigenetic marks: DNA methylation and histone H3 lysine 9 methylation
LM Johnson, X Cao, SE Jacobsen - Current Biology, 2002 - cell.com
Background: The heterochromatin of many eukaryotes is marked by both DNA methylation
and histone H3 lysine 9 (H3-K9) methylation, though the exact relationship between these …
and histone H3 lysine 9 (H3-K9) methylation, though the exact relationship between these …
HP1 is essential for DNA methylation in Neurospora
Methylation of cytosines silences transposable elements and selected cellular genes in
mammals, plants, and some fungi. Recent findings have revealed mechanistic connections …
mammals, plants, and some fungi. Recent findings have revealed mechanistic connections …
Erasure of CpG methylation in Arabidopsis alters patterns of histone H3 methylation in heterochromatin
In mammals and plants, formation of heterochromatin is associated with hypermethylation of
DNA at CpG sites and histone H3 methylation at lysine 9. Previous studies have revealed …
DNA at CpG sites and histone H3 methylation at lysine 9. Previous studies have revealed …
Dimethylation of histone H3 lysine 9 is a critical mark for DNA methylation and gene silencing in Arabidopsis thaliana
JP Jackson, L Johnson, Z Jasencakova, X Zhang… - Chromosoma, 2004 - Springer
The Arabidopsis KRYPTONITE gene encodes a member of the Su (var) 3-9 family of histone
methyltransferases. Mutations of kryptonite cause a reduction of methylated histone H3 …
methyltransferases. Mutations of kryptonite cause a reduction of methylated histone H3 …
Direct Interaction between DNA Methyltransferase DIM-2 and HP1 Is Required for DNA Methylation in Neurospora crassa
DNA methylation is involved in gene silencing and genomic stability in mammals, plants,
and fungi. Genetics studies of Neurospora crassa have revealed that a DNA …
and fungi. Genetics studies of Neurospora crassa have revealed that a DNA …
Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain
Abstract Heterochromatin protein 1 (HP1) is localized at heterochromatin sites where it
mediates gene silencing,. The chromo domain of HP1 is necessary for both targeting and …
mediates gene silencing,. The chromo domain of HP1 is necessary for both targeting and …
Control of DNA methylation and heterochromatic silencing by histone H2B deubiquitination
Epigenetic regulation involves reversible changes in DNA methylation and/or histone
modification patterns,,,,,,. Short interfering RNAs (siRNAs) can direct DNA methylation and …
modification patterns,,,,,,. Short interfering RNAs (siRNAs) can direct DNA methylation and …
Dual histone H3 methylation marks at lysines 9 and 27 required for interaction with CHROMOMETHYLASE3
AM Lindroth, D Shultis, Z Jasencakova, J Fuchs… - The EMBO …, 2004 - embopress.org
Both DNA methylation and post‐translational histone modifications contribute to gene
silencing, but the mechanistic relationship between these epigenetic marks is unclear …
silencing, but the mechanistic relationship between these epigenetic marks is unclear …