Epigenetic modifications characterized by DNA methylation, histone modifications, and
chromatin remodeling are important regulators in a number of biological processes …

Recent studies have indicated that epigenetic alterations are critical for normal function and
development of spermatozoa during the fertilization process. This review will focus on the …

Infertility is a complex disorder with multiple genetic and environmental causes. Although
some specific mutations have been identified, other factors responsible for sperm defects …

Infertility is a significant problem for human reproduction, with males and females equally
affected. However, the molecular mechanisms underlying male infertility remain unclear …

During the last decades the study of male infertility and the introduction of the assisted
reproductive techniques (ARTs) has allowed to understand that normal sperm parameters …

Male infertility is a common and complex problem affecting 1 in 20 men. Despite voluminous
research in this field, in many cases, the underlying causes are unknown. Epigenetic factors …

Background Male-factor infertility is a common condition, and etiology is unknown for a high
proportion of cases. Abnormal epigenetic programming of the germline is proposed as a …

Infertility is an often devastating diagnosis encountered by around one in six couples who
are trying to conceive. Moving away from the long-held belief that infertility is primarily a …

Along with many of the genome-wide transitions in chromatin composition throughout
spermatogenesis, epigenetic modifications on histone tails and DNA are continuously …

In recent years, a number of studies focused on the role of epigenetics, including DNA
methylation, in spermatogenesis and male infertility. We aimed to provide an overview of the …