Thrombotic thrombocytopenic purpura

JA Kremer Hovinga, P Coppo, B Lämmle… - Nature reviews Disease …, 2017 - nature.com
Thrombotic thrombocytopenic purpura (TTP; also known as Moschcowitz disease) is
characterized by the concomitant occurrence of often severe thrombocytopenia …

Role of ADAMTS13 in the pathogenesis, diagnosis, and treatment of thrombotic thrombocytopenic purpura

JAK Hovinga, B Lämmle - Hematology 2010, the American …, 2012 - ashpublications.org
The regulation of VWF multimer size is essential in preventing spontaneous microvascular
platelet clumping, a central pathophysiologic finding in thrombotic thrombocytopenic …

Thrombotic thrombocytopenic purpura: basic pathophysiology and therapeutic strategies

JTB Crawley, MA Scully - Hematology 2013, the American …, 2013 - ashpublications.org
VWF is a multimeric plasma glycoprotein that specifically recruits platelets to sites of vessel
injury. VWF multimeric size is central to this function, with larger multimers being more …

Thrombotic thrombocytopenic purpura

BS Joly, P Coppo, A Veyradier - Blood, The Journal of the …, 2017 - ashpublications.org
Thrombotic thrombocytopenic purpura (TTP) is a rare and life-threatening thrombotic
microangiopathy characterized by microangiopathic hemolytic anemia, severe …

Recent advances in thrombotic thrombocytopenic purpura

JE Sadler, JL Moake, T Miyata… - ASH Education Program …, 2004 - ashpublications.org
Thrombotic thrombocytopenic purpura (TTP) is characterized by microangiopathic hemolytic
anemia and thrombocytopenia, accompanied by microvascular thrombosis that causes …

An update on pathogenesis and diagnosis of thrombotic thrombocytopenic purpura

BS Joly, P Coppo, A Veyradier - Expert review of hematology, 2019 - Taylor & Francis
Introduction: Thrombotic thrombocytopenic purpura (TTP) is a rare and life-threatening
thrombotic microangiopathy characterized by microangiopathic hemolytic anemia …

How I treat refractory thrombotic thrombocytopenic purpura

FA Sayani, CS Abrams - Blood, The Journal of the American …, 2015 - ashpublications.org
Acquired thrombotic thrombocytopenic purpura (TTP) is characterized by thrombocytopenia
and microangiopathic hemolytic anemia (MAHA) without an obvious cause, and may include …

Pathophysiology of thrombotic thrombocytopenic purpura

HM Tsai - International journal of hematology, 2010 - Springer
Thrombotic thrombocytopenic purpura (TTP) is a disorder with characteristic von Willebrand
factor (VWF)-rich microthrombi affecting the arterioles and capillaries of multiple organs. The …

Thrombotic thrombocytopenic purpura-then and now

M Noris, G Remuzzi - Seminars in thrombosis and hemostasis, 2006 - thieme-connect.com
Thrombotic thrombocytopenic purpura (TTP) is a potentially life-threatening disease
characterized by microangiopathic hemolytic anemia, thrombocytopenia, and formation of …

Management of thrombotic thrombocytopenic purpura: current perspectives

P Blombery, M Scully - Journal of blood medicine, 2014 - Taylor & Francis
Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening thrombotic
microangiopathy which causes significant morbidity and mortality unless promptly …