ACE inhibition in aortic stenosis: dangerous medicine or golden opportunity?

HC Routledge, JN Townend - Journal of human hypertension, 2001 - nature.com
Conventionally angiotensin-converting enzyme (ACE) inhibitors are contraindicated in
patients with aortic stenosis. Abundant evidence is now available showing that angiotensin II …

Safety and efficacy of angiotensin-converting enzyme inhibitors in symptomatic severe aortic stenosis: symptomatic cardiac obstruction–pilot study of enalapril in aortic …

A Chockalingam, S Venkatesan, T Subramaniam… - American heart …, 2004 - Elsevier
BACKGROUND: Animal models have demonstrated a benefit of angiotensin-converting
enzyme inhibitors (ACEI) in experimental aortic stenosis (AS), and intravenous nitroprusside …

Hypertension and aortic stenosis: a review

A Rassa, F Zahr - Current hypertension reviews, 2018 - ingentaconnect.com
Background: Aortic stenosis is a common form of valvular heart disease which often coexists
with hypertension. These diseases represent two distinct forms of left ventricular systolic …

Effects of angiotensin converting enzyme inhibitors in hypertensive patients with aortic valve stenosis: a drug withdrawal study

J Jimenez-Candil, J Bermejo, R Yotti, C Cortina… - Heart, 2005 - heart.bmj.com
Objective: To determine the effects of angiotensin converting enzyme (ACE) inhibitors in
hypertensive patients with aortic valve stenosis (AS). Design: Observational, drug …

Hemodynamic effects of the angiotensin-converting enzyme inhibitor, ramipril, in patients with mild to moderate aortic stenosis and preserved left ventricular function

KD O'Brien, XQ Zhao, DM Shavelle… - Journal of …, 2004 - journals.sagepub.com
Background Angiotensin-converting enzyme (ACE) inhibitor use is presumed to be
contraindicated in patients with aortic stenosis (AS). We determined the hemodynamic …

ACE inhibitors in vascular disease: some PROGRESS, more HOPE.

GYH Lip, DG Beevers - Journal of Human Hypertension, 2001 - search.ebscohost.com
Focuses on the role of angiotensin converting enzyme (ACE) inhibitors in vascular diseases.
Use of angiotensin in the treatment of various diseases; Significance of antihypertensive …

Antiatherosclerotic effects of ACE inhibitors: where are we now?

E Lonn - American Journal of Cardiovascular Drugs, 2001 - Springer
ACE inhibitors have been used extensively in the management of patients with hypertension
and heart failure. Over the past decade, a large body of evidence has emerged indicating …

Short-term hemodynamic effect of angiotensin-converting enzyme inhibition in patients with severe aortic stenosis: a placebo-controlled, randomized study

M Dalsgaard, K Iversen, J Kjaergaard, P Grande… - American Heart …, 2014 - Elsevier
Background In patients with severe aortic stenosis (AS), treatment with angiotensin-
converting enzyme inhibitors has previously been considered contraindicated. However …

Modulating atherosclerosis through inhibition or blockade of angiotensin

RS Rosenson - … Cardiology: An International Indexed and Peer …, 2003 - Wiley Online Library
Angiotensin‐converting enzyme (ACE) inhibitors are well recognized for their benefits in
treating hypertension and congestive heart failure and preventing postmyocardial infarction …

A prospective, double-blind, randomized controlled trial of the angiotensin-converting enzyme inhibitor Ramipril In Aortic Stenosis (RIAS trial)

S Bull, M Loudon, JM Francis, J Joseph… - European Heart …, 2015 - academic.oup.com
Aims Angiotensin-converting enzyme (ACE) inhibitors improve left ventricular (LV)
remodelling and outcome in heart failure and hypertensive heart disease. They may be …