The purpose of this systematic review was to evaluate the effects of physiotherapeutic
interventions on biomarkers of neuropathic pain in preclinical models of peripheral …

Background The treatment of neuropathic pain remains a major unmet need that the
development of personalized and refined treatment strategies may contribute to address …

Neuropathic pain encompasses a broad range of conditions associated with a lesion or
disease of the peripheral or central somatosensory system and its prevalence in the general …

This preclinical systematic review aimed to determine the effectiveness of different types and
doses of exercise on pain behavior and biomarkers in preclinical models of focal …

Abstract The International Association for the Study of Pain defines neuropathic pain as
“pain arising as a direct consequence of a lesion or disease affecting the somatosensory …

Results. There was high variability in the pain-time trend in response to continuous noxious
electric stimulation with constant intensity between volunteers. During 10min of stimulation …

Patients with neuropathic pain are heterogeneous in etiology, pathophysiology, and clinical
appearance. They exhibit a variety of painrelated sensory symptoms and signs (sensory …

Neuropathic pain is a common problem in clinical practice and one that adversely affects
patients' quality of life. Converging evidence from animal and human studies demonstrates …

Over the last three decades, the number of research studies devoted to neuropathic pain
has increased dramatically. This expansion of knowledge has generated a number of …

Neuropathic pain remains poorly treated, with most new drugs falling through the
translational gap. The traditional model of bench-to-bedside research has relied on …