Aortic aneurysm (AA) is a vascular disorder characterized pathologically by inflammatory
cell invasion and extracellular matrix (ECM) degradation. It is known that regulation of the …

BACKGROUND: The aim of this study was to evaluate alterations in Th1 and Th2 cytokines
during experimental abdominal aortic aneurysm (AAA) formation. METHODS: AAAs were …

Objective—Abdominal aortic aneurysm (AAA) is widespread among elderly people and
results in progressive expansion and rupture of the aorta with high mortality. Macrophages …

Mesenchymal stem cells (MSCs) exhibit therapeutic benefits on aortic aneurysm (AA);
however, the molecular mechanisms are not fully understood. The current study aimed to …

Objective—The presence of apoptotic markers is a prominent histological feature of
abdominal aortic aneurysm. To understand the role of apoptosis in the pathogenesis of this …

Background and Purpose To test the hypothesis that angiotensin‐(1‐7)[Ang‐(1‐7)] may
attenuate abdominal aortic aneurysm (AAA) via inhibiting vascular inflammation …

Angiotensin II (AngII) infusion initiates abdominal aortic aneurysm (AAA) development due
to medial disruption and results in luminal dilation and thrombus formation. The objective of …

Abdominal aortic aneurysm (AAA) is an enlargement of the aorta greater than 50% in
diameter. Although up to 80% of cases result in mortality if the aneurysm ruptures, patients …

OBJECTIVE: Aortic aneurysm (AA) is associated with loss of elastin and structural integrity,
accompanied by increased matrix metalloproteinase (MMP) expression. These processes …

Objective: Aortic macrophage accumulation is characteristic of the pathogenesis of
abdominal aortic aneurysm (AAA) but the mechanisms of macrophage accumulation and …