Trichosporon asahii is a conditional pathogenic fungus that causes severe and sometimes
fatal infections in immunocompromised patients. While calcineurin, an essential component …

Calcineurin is highly conserved and regulates growth, conidiation, stress response, and
pathogenicity in fungi. However, the functions of calcineurin and its regulatory network in …

Calcineurin signaling plays diverse roles in fungi in regulating stress responses,
morphogenesis and pathogenesis. Although calcineurin signaling is conserved among …

Trichosporon asahii is a pathogenic fungus that causes severe, deep-seated fungal
infections in neutropenic patients. Elucidating the infection mechanisms of T. asahii based …

Magnaporthe oryzae, the causal agent of rice blast, forms a specialized infection structure,
called an appressorium, which is crucial for penetration and infection of the host plant …

Calcineurin is a calcium-activated phosphatase that controls morphogenesis and stress
responses in eukaryotes. Fungal pathogens have adopted the calcineurin pathway to …

The serine-threonine-specific protein phosphatase calcineurin is a key mediator of various
stress responses in fungi. Herein, we characterized functions of the endogenous regulators …

Calcium is an abundant intracellular ion, and calcium homeostasis plays crucial roles in
several cellular processes. The calcineurin signaling cascade is one of the major pathways …

Candida tropicalis, a species closely related to Candida albicans, is an emerging fungal
pathogen associated with high mortality rates of 40 to 70%. Like C. albicans and Candida …

Calcineurin governs stress survival, sexual differentiation, and virulence of the human fungal
pathogen Cryptococcus neoformans. Calcineurin is activated by increased Ca2+ levels …