Non-BOLD contrast for laminar fMRI in humans: CBF, CBV, and CMRO2

L Huber, K Uludağ, HE Möller - Neuroimage, 2019 - Elsevier
Functional magnetic resonance imaging (fMRI) using the blood oxygenation level-
dependent (BOLD) contrast indirectly probes neuronal activity changes via evoked cerebral …

[HTML][HTML] Linking brain vascular physiology to hemodynamic response in ultra-high field MRI

K Uludağ, P Blinder - Neuroimage, 2018 - Elsevier
Functional MRI using blood oxygenation level-dependent (BOLD) contrast indirectly probes
neuronal activity via evoked cerebral blood volume (CBV) and oxygenation changes. Thus …

Noninvasive functional imaging of cerebral blood volume with vascular‐space‐occupancy (VASO) MRI

H Lu, J Hua, PCM van Zijl - NMR in Biomedicine, 2013 - Wiley Online Library
Functional MRI (fMRI) based on changes in cerebral blood volume (CBV) can probe directly
vasodilatation and vasoconstriction during brain activation or physiologic challenges, and …

Strategies and prospects for cortical depth dependent T2 and T2* weighted BOLD fMRI studies

PJ Koopmans, E Yacoub - Neuroimage, 2019 - Elsevier
Technological advancements in fMRI have afforded the opportunity to conduct submillimeter
investigations into human brain function. The ability to do cortical depth dependent (or layer …

The effect of labeling parameters on perfusion-based fMRI in nonhuman primates

AC Zappe, J Pfeuffer, H Merkle… - Journal of Cerebral …, 2008 - journals.sagepub.com
The blood oxygenation level-dependent (BOLD) signal is the most commonly used modality
of functional magnetic resonance imaging (fMRI) today. Although easy to implement, it is an …

Quantitative functional MRI: concepts, issues and future challenges

GB Pike - Neuroimage, 2012 - Elsevier
Since its inception 20years ago, functional magnetic resonance imaging (fMRI) of the human
brain based on the blood oxygenation level dependent (BOLD) contrast phenomenon has …

Comparing cerebrovascular reactivity measured using BOLD and cerebral blood flow MRI: The effect of basal vascular tension on vasodilatory and vasoconstrictive …

S Halani, JB Kwinta, AM Golestani, YB Khatamian… - Neuroimage, 2015 - Elsevier
Cerebrovascular reactivity (CVR) is an important metric of cerebrovascular health. While the
BOLD fMRI method in conjunction with carbon-dioxide (CO 2) based vascular manipulation …

Biophysical and physiological origins of blood oxygenation level-dependent fMRI signals

SG Kim, S Ogawa - Journal of Cerebral Blood Flow & …, 2012 - journals.sagepub.com
After its discovery in 1990, blood oxygenation level-dependent (BOLD) contrast in functional
magnetic resonance imaging (fMRI) has been widely used to map brain activation in …

Technical aspects and utility of fMRI using BOLD and ASL

JA Detre, J Wang - Clinical Neurophysiology, 2002 - Elsevier
Functional magnetic resonance imaging (fMRI) is an emerging methodology which provides
various approaches to visualizing regional brain activity non-invasively. Although the exact …

On the nature of the BOLD fMRI contrast mechanism

NK Logothetis, J Pfeuffer - Magnetic resonance imaging, 2004 - Elsevier
Since its development about 15 years ago, functional magnetic resonance imaging (fMRI)
has become the leading research tool for mapping brain activity. The technique works by …