Mast cells (MCs) regulate inflammation and immunity. Their granular content includes
heparin, histamine, and several enzymes (tryptase, chymase, carboxypeptidase, and …

Mast cells (MCs) are proinflammatory cells that play important roles in allergic responses,
tumor growth, obesity, diabetes, atherosclerosis, and abdominal aortic aneurysm (AAA) …

OBJECTIVE: Mast cells (MCs) are inflammatory cells present in atherosclerotic lesions and
neovascularized tissues. Recently, MCs were shown to modulate abdominal aortic …

Mast cells (MCs) are implicated in the pathogenesis of atherosclerosis and abdominal aortic
aneurysm (AAA). MC-specific chymase and tryptase play important roles in inducing …

Abdominal aortic aneurysm (AAA), an inflammatory disease, involves leukocyte recruitment,
immune responses, inflammatory cytokine production, vascular remodeling …

Abdominal aortic aneurysm (AAA) is histologically characterized by medial degeneration
and various degrees of chronic adventitial inflammation, although the mechanisms for …

Aims Mast cells participate importantly in abdominal aortic aneurysms (AAAs) by releasing
inflammatory cytokines to promote vascular cell protease expression and arterial wall …

Mast cells (MC) are granulated secretory cells that have long been recognized as a rich
source of biologically highly active mediators such as biogenic amines, prostaglandins …

Background—Mast cell chymase may participate in the pathogenesis of human abdominal
aortic aneurysm (AAA), yet a direct contribution of this serine protease to AAA formation …

Mast cells, like many other types of inflammatory cell, perform pleiotropic roles in
cardiometabolic diseases such as atherosclerosis, abdominal aortic aneurysms, obesity …