MicroRNAs (miRNAs) are small non-coding RNAs that regulate post-transcriptional gene
expression by targeting specific mRNAs for degradation or translation repression. Changes …

Tauopathies are neurodegenerative disorders which include Alzheimer's disease, Pick's
disease, corticobasal degeneration, and progressive supranuclear palsy among others …

Abnormal regulation of tau phosphorylation and/or alternative splicing is associated with the
development of a large (> 20) group of neurodegenerative disorders collectively known as …

Tau is a highly abundant and multifunctional brain protein that accumulates in neurofibrillary
tangles (NFTs), most commonly in Alzheimer's disease (AD) and primary age-related …

Background and Objective: Alzheimer's disease (AD) is arguably the largest healthcare
issue of our time. AD is thought to be principally the result of an inter-play between the β …

Abstract microRNAs (miRNAs) are small, noncoding RNA molecules that through imperfect
base-pairing with complementary sequences of target mRNA molecules, typically cleave …

Tauopathies are a group of neurodegenerative diseases characterised by intracellular
deposits of the microtubule-associated protein tau. The most typical example of a tauopathy …

Abstract MicroRNAs (miRs) are 18~ 23 nucleotides long non-coding RNAs that regulate
gene expression. To explore whether miR alterations in tauopathy contribute to pathological …

Studies have shown that the expression level of different microRNAs (miRNAs) is altered in
neurodegenerative disorders including tauopathies, a group of diseases pathologically …

Alzheimer's disease (AD), with main clinical features of progressive impairment in cognitive
and behavioral functions, is the most common degenerative disease of the central nervous …