Chronic exposure to high altitude: synaptic, astroglial and memory changes

R Sharma, NP Cramer, B Perry, Z Adahman… - Scientific Reports, 2019 - nature.com
Long-term operations carried out at high altitude (HA) by military personnel, pilots, and
astronauts may trigger health complications. In particular, chronic exposure to high altitude …

[HTML][HTML] Neuronal and vascular deficits following chronic adaptation to high altitude

NP Cramer, A Korotcov, A Bosomtwi, X Xu… - Experimental …, 2019 - Elsevier
We sought to understand the mechanisms underlying cognitive deficits that are reported to
affect non-native subjects following their prolonged stay and/or work at high altitude (HA) …

Cognitive changes during prolonged stay at high altitude and its correlation with C-reactive protein

SL Hu, W Xiong, ZQ Dai, HL Zhao, H Feng - PLoS One, 2016 - journals.plos.org
Hypersensitive C-reaction protein (hsCRP) may be a risk factor for cognitive impairment
resulting from Alzheimer's disease (AD), stroke, and vascular dementia. This study explored …

High altitude memory impairment is due to neuronal apoptosis in hippocampus, cortex and striatum

P Maiti, SB Singh, B Mallick, S Muthuraju… - Journal of chemical …, 2008 - Elsevier
Cognitive and neuropsychological functions have been impaired at high altitude and the
effects depend on altitude and duration of stay. However, the neurobiological mechanism of …

[HTML][HTML] Association of peripheral plasma neurotransmitters with cognitive performance in chronic high-altitude exposure

Z Zhong, S Zhou, B Xiang, Y Wu, J Xie, P Li - Neuroscience, 2021 - Elsevier
Long-term living at high altitude causes significant impairment of cognitive function. Central
neurotransmitters are potential mediators of cognitive performance. We aimed to determine …

Hypobaric hypoxia induces dendritic plasticity in cortical and hippocampal pyramidal neurons in rat brain

P Maiti, S Muthuraju, G Ilavazhagan… - Behavioural brain research, 2008 - Elsevier
Hypobaric hypoxia (HH), a predisposing environmental condition at high altitude (HA)
encountered by many mountaineers jeopardizes their normal physiology like motor …

Reversible brain abnormalities in people without signs of mountain sickness during high-altitude exposure

C Fan, Y Zhao, Q Yu, W Yin, H Liu, J Lin, T Yang… - Scientific reports, 2016 - nature.com
A large proportion of lowlanders ascending to high-altitude (HA) show no signs of mountain
sickness. Whether their brains have indeed suffered from HA environment and the persistent …

Insight into the Effects of High‐Altitude Hypoxic Exposure on Learning and Memory

Z Zhang, Y Sun, Z Yuan, L Wang… - Oxidative Medicine …, 2022 - Wiley Online Library
The earth land area is heterogeneous in terms of elevation; about 45% of its land area
belongs to higher elevation with altitude above 500 meters compared to sea level. In most …

Hypobaric hypoxia damages the hippocampal pyramidal neurons in the rat brain

P Maiti, SB Singh, S Muthuraju, S Veleri, G Ilavazhagan - Brain research, 2007 - Elsevier
Hypobaric hypoxia (HH), a predisposing environmental condition at high altitude (HA),
encountered by many mountaineers, jeopardizes their normal physiology like motor …

Temporal and spatial changes in glial cells during chronic hypobaric hypoxia: role in neurodegeneration

A Dheer, V Jain, N Kushwah, R Kumar, D Prasad… - Neuroscience, 2018 - Elsevier
Ascend to high altitude results in a drastic change in the environmental conditions an
individual is exposed to. As the altitude increases there is a decrease in partial pressure of …