A novel H19 antisense RNA overexpressed in breast cancer contributes to paternal IGF2 expression
N Berteaux, N Aptel, G Cathala, C Genton… - … and cellular biology, 2008 - Am Soc Microbiol
The H19/IGFf2 locus belongs to a large imprinted domain located on human chromosome
11p15. 5 (homologue to mouse distal chromosome 7). The H19 gene is expressed from the …
11p15. 5 (homologue to mouse distal chromosome 7). The H19 gene is expressed from the …
H19 Antisense RNA Can Up-Regulate Igf2 Transcription by Activation of a Novel Promoter in Mouse Myoblasts
VG Tran, F Court, A Duputie, E Antoine, N Aptel… - PLoS …, 2012 - journals.plos.org
It was recently shown that a long non-coding RNA (lncRNA), that we named the 91H RNA
(ie antisense H19 transcript), is overexpressed in human breast tumours and contributes in …
(ie antisense H19 transcript), is overexpressed in human breast tumours and contributes in …
Regulatory Mechanisms at the MouseIgf2/H19 Locus
CR Kaffer, A Grinberg, K Pfeifer - Molecular and cellular biology, 2001 - Taylor & Francis
The closely linked H19 and Igf2 genes show highly similar patterns of gene expression but
are reciprocally imprinted. H19 is expressed almost exclusively from the maternally inherited …
are reciprocally imprinted. H19 is expressed almost exclusively from the maternally inherited …
The long non-coding RNA 91H increases aggressive phenotype of breast cancer cells and up-regulates H19/IGF2 expression through epigenetic modifications
C Vennin, N Spruyt, YM Robin, T Chassat… - Cancer letters, 2017 - Elsevier
Numerous genomic imprinting loci are regulated by long non-coding RNA (lncRNA). We
have previously identified a new lncRNA at the H19/IGF2 locus transcribed in H19 antisense …
have previously identified a new lncRNA at the H19/IGF2 locus transcribed in H19 antisense …
Biallelic transcription of Igf2 and H19 in individual cells suggests a post-transcriptional contribution to genomic imprinting
Y Jouvenot, F Poirier, J Jami, A Paldi - Current Biology, 1999 - cell.com
The H19 and insulin-like growth factor 2 (Igf2) genes in the mouse are models for genomic
imprinting during development. The genes are located only 90 kb apart in the same …
imprinting during development. The genes are located only 90 kb apart in the same …
H19 acts as a trans regulator of the imprinted gene network controlling growth in mice
A Gabory, MA Ripoche, A Le Digarcher… - …, 2009 - journals.biologists.com
The imprinted H19 gene produces a non-coding RNA of unknown function. Mice lacking
H19 show an overgrowth phenotype, due to a cis effect of the H19 locus on the adjacent Igf2 …
H19 show an overgrowth phenotype, due to a cis effect of the H19 locus on the adjacent Igf2 …
Enhancer competition between H19 and Igf2 does not mediate their imprinting
JV Schmidt, JM Levorse… - Proceedings of the …, 1999 - National Acad Sciences
The linked H19 and Igf2 genes on mouse distal chromosome 7 are subject to genomic
imprinting. Competition between the promoters of the genes for transcription from shared …
imprinting. Competition between the promoters of the genes for transcription from shared …
Multiple imprinted sense and antisense transcripts, differential methylation and tandem repeats in a putative imprinting control region upstream of mouse Igf2
T Moore, M Constancia, M Zubair… - Proceedings of the …, 1997 - National Acad Sciences
The mouse insulin-like growth factor 2 (Igf2) locus is a complex genomic region that
produces multiple transcripts from alternative promoters. Expression at this locus is …
produces multiple transcripts from alternative promoters. Expression at this locus is …
[HTML][HTML] Role of histone acetylation and DNA methylation in the maintenance of the imprinted expression of the H19 and Igf2 genes
PV Pedone, MJ Pikaart, F Cerrato, M Vernucci… - FEBS letters, 1999 - Elsevier
H19 and Igf2 are linked and reciprocally imprinted genes. We demonstrate that the histones
associated with the paternally inherited and unexpressed H19 allele are less acetylated …
associated with the paternally inherited and unexpressed H19 allele are less acetylated …
Comparative analysis of Igf-2/H19 imprinted domain: identification of a highly conserved intergenic DNase I hypersensitive region
T Koide, J Ainscough, M Wijgerde, MA Surani - Genomics, 1994 - Elsevier
The closely linked, reciprocally imprinted mouse genes, insulin-like growth factor II (Igf-2)
and H19, provide a significant paradigm for studies of the mechanism of parental imprinting …
and H19, provide a significant paradigm for studies of the mechanism of parental imprinting …