Role of extracellular matrix and inflammation in abdominal aortic aneurysm

KL Stepien, K Bajdak-Rusinek, A Fus-Kujawa… - International journal of …, 2022 - mdpi.com
Abdominal aortic aneurysm (AAA) is one of the most dangerous cardiovascular diseases,
occurring mainly in men over the age of 55 years. As it is asymptomatic, patients are …

Circulating biomarkers and abdominal aortic aneurysm size

FA Hellenthal, B Pulinx, JTJ Rob, JAW Teijink… - Journal of Surgical …, 2012 - Elsevier
BACKGROUND: Abdominal aortic aneurysm (AAA) is a degenerative disease of the
abdominal aorta leading to progressive dilatation, intra-luminal thrombus (ILT) formation …

Dysregulations of key regulators of angiogenesis and inflammation in abdominal aortic aneurysm

D Zalewski, P Chmiel, P Kołodziej, G Borowski… - International Journal of …, 2023 - mdpi.com
Abdominal aortic aneurysm (AAA) is a chronic vascular disease caused by localized
weakening and broadening of the abdominal aorta. AAA is a clearly underdiagnosed …

Inflammation in abdominal aortic aneurysms: cellular infiltrate and cytokine profiles

MJ Eagleton - Vascular, 2012 - journals.sagepub.com
Abdominal aortic aneurysm (AAA) pathogenesis occurs as a result of the altered
homeostasis of the aortic vessel wall structural proteins. This results in weakening, and …

Aortic wall inflammation in the pathogenesis, diagnosis and treatment of aortic aneurysms

G Skotsimara, A Antonopoulos, E Oikonomou… - Inflammation, 2022 - Springer
The role of inflammation in the development of aortic aneurysms is emerging, along with the
potential diagnostic and therapeutical potential of this correlation. Abdominal aorta …

Cytokines in abdominal aortic aneurysm: master regulators with clinical application

OA Puchenkova, VO Soldatov, AE Belykh… - Biomarker …, 2022 - journals.sagepub.com
Abdominal aortic aneurysm (AAA) is a potentially life-threatening disorder with a mostly
asymptomatic course where the abdominal aorta is weakened and bulged. Cytokines play …

Monocytes and macrophages in abdominal aortic aneurysm

J Raffort, F Lareyre, M Clément… - Nature Reviews …, 2017 - nature.com
Abdominal aortic aneurysm (AAA) is a life-threatening disease associated with high
morbidity, and high mortality in the event of aortic rupture. Major advances in open surgical …

Profile of macrophages in human abdominal aortic aneurysms: a transcriptomic, proteomic, and antibody protein array study

N Lamblin, P Ratajczak, D Hot, E Dubois… - Journal of proteome …, 2010 - ACS Publications
Abdominal aortic aneurysms (AAA) are defined by an increased aortic diameter and
characterized by impairment of the extracellular matrix, macrophages infiltration and …

Inflammatory cells and proteases in abdominal aortic aneurysm and its complications

H Jiang, T Sasaki, E Jin, M Kuzuya… - Current Drug …, 2018 - ingentaconnect.com
Abdominal aortic aneurysm (AAA), a common disease among elderly individuals, involves
the progressive dilatation of the abdominal aorta as a consequence of degeneration. The …

Abdominal aortic aneurysm: roles of inflammatory cells

Z Yuan, Y Lu, J Wei, J Wu, J Yang, Z Cai - Frontiers in immunology, 2021 - frontiersin.org
Abdominal aortic aneurysms (AAAs) are local dilations of infrarenal segment of aortas.
Molecular mechanisms underlying the pathogenesis of AAA remain not fully clear. However …