Tranexamic acid: from trauma to routine perioperative use
J Simmons, RA Sikorski, JF Pittet - Current Opinion in …, 2015 - journals.lww.com
Tranexamic acid: from trauma to routine perioperative use : Current Opinion in
Anesthesiology Tranexamic acid: from trauma to routine perioperative use : Current Opinion …
Anesthesiology Tranexamic acid: from trauma to routine perioperative use : Current Opinion …
Tranexamic acid: still far to go
SM Goobie - BJA: British Journal of Anaesthesia, 2017 - academic.oup.com
Tranexamic acid (TXA), a synthetic lysine analogue, is a potent antifibrinolytic agent that
inhibits both plasminogen and plasmin. Tranexamic acid gained worldwide recognition in …
inhibits both plasminogen and plasmin. Tranexamic acid gained worldwide recognition in …
Update on applications and limitations of perioperative tranexamic acid
PA Patel, JA Wyrobek, AJ Butwick… - Anesthesia & …, 2022 - journals.lww.com
Tranexamic acid (TXA) is a potent antifibrinolytic with documented efficacy in reducing blood
loss and allogeneic red blood cell transfusion in several clinical settings. With a growing …
loss and allogeneic red blood cell transfusion in several clinical settings. With a growing …
Intraoperative tranexamic acid use in major spine surgery in adults: a multicentre, randomized, placebo-controlled trial
MJ Colomina, M Koo, M Basora… - BJA: British Journal …, 2017 - academic.oup.com
Background. Perioperative tranexamic acid (TXA) use can reduce bleeding and transfusion
requirements in several types of surgery, but level I evidence proving its effectiveness in …
requirements in several types of surgery, but level I evidence proving its effectiveness in …
Prophylactic tranexamic acid use in non‐cardiac surgeries at high risk for transfusion
BL Houston, DA Fergusson, J Falk… - Transfusion …, 2021 - Wiley Online Library
Background Tranexamic acid (TXA) reduces transfusion in a wide range of surgical
populations, although its real‐world use in non‐cardiac surgeries has not been well …
populations, although its real‐world use in non‐cardiac surgeries has not been well …
Tranexamic acid: what is known and unknown, and where do we go from here?
experts at drug dosing, and we likely have more experience doing so than any other
specialty in medicine. With anesthetic drugs such as fentanyl or propofol, we often dose by …
specialty in medicine. With anesthetic drugs such as fentanyl or propofol, we often dose by …
Systematic review, meta-analysis and meta-regression of the effect of tranexamic acid on surgical blood loss
K Ker, D Prieto-Merino, I Roberts - Journal of British Surgery, 2013 - academic.oup.com
Background Tranexamic acid (TXA) reduces blood transfusion in surgery but the extent of
the reduction in blood loss and how it relates to the dose of TXA is unclear. Methods A …
the reduction in blood loss and how it relates to the dose of TXA is unclear. Methods A …
Exclusion criteria and adverse events in perioperative trials of tranexamic acid: a systematic review and meta‐analysis
J Yates, I Perelman, S Khair, J Taylor, J Lampron… - …, 2019 - Wiley Online Library
BACKGROUND Tranexamic acid (TXA) is an inexpensive therapy effective at minimizing
perioperative blood loss and transfusion. However, it remains underutilized due to safety …
perioperative blood loss and transfusion. However, it remains underutilized due to safety …
Clinical use of tranexamic acid: evidences and controversies
MJ Colomina, L Contreras, P Guilabert… - Brazilian journal of …, 2022 - SciELO Brasil
Tranexamic acid (TXA) significantly reduces blood loss in a wide range of surgical
procedures and improves survival rates in obstetric and trauma patients with severe …
procedures and improves survival rates in obstetric and trauma patients with severe …
Tranexamic Acid in Anesthetic Management of Surgical Procedures.
J Mayeux - AANA journal, 2016 - search.ebscohost.com
Blood loss during surgical procedures poses a grave risk to the patient, but transfusion is
costly and associated with adverse outcomes. Antifibrinolytics, however, offer an economical …
costly and associated with adverse outcomes. Antifibrinolytics, however, offer an economical …
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