Cisplatin-related ototoxicity is a critical side effect of chemotherapy and can lead to
irreversible hearing loss. This study aimed to assess the potential effect of the DNA …

Cisplatin is a well-known and commonly used chemotherapeutic agent. However, cisplatin-
induced ototoxicity limits its clinical use. Previous studies have shown an important role of …

Deafness is the most common sensory disorder in the world. Ototoxic drugs are common
inducing factors of sensorineural hearing loss, and cochlear hair cell (HC) damage is the …

Hearing loss is the most common sensory disorder in humans, and a significant number of
cases is due to the ototoxicity of drugs such as cisplatin that cause hair cell (HC) damage …

Cisplatin‐induced ototoxicity is one of the common side effects during its treatment and there
are no effective measures to prevent it. Our study aimed to investigate the effect of ACSL4 …

Cisplatin is an antitumor drug that is widely used for the treatment of various solid tumors.
Unfortunately, patients are often troubled by serious side effects, especially hearing loss. Up …

Background Cisplatin-induced ototoxicity affects a high percentage of new cancer patients
worldwide. The detailed mechanism of cisplatin-induced ototoxicity is not completely …

Cis-diamminedichloridoplatinum (II)(cisplatin) is a chemotherapeutic drug currently
prescribed for the treatment of many types of human cancer, but its use is associated with …

Cisplatin is a widely used chemotherapeutic drug for the treatment of various cancers.
However, the ototoxicity severely limited its maximum dose. The present study was designed …

Cisplatin, a chemotherapeutic agent for treating various solid tumors, produces hearing loss
in approximately half a million cancer patients annually in the United States. In the course of …