methylcytosine (5mC) is an epigenetic mark which has a profound effect on various
fundamental processes in cells. In present study, at first Hydrophilic Interaction Liquid …

A hydrophilic interaction chromatography-based method, in combination with 1.7 µm
ethylene bridged hybrid particle packed column (100 mm× 2.1 mm ID) and ultraperformance …

Methylation of DNA at the 5-position of cytosine (Cyt) is a well-studied epigenetic pathway
implicated in gene silencing and embryogenesis. Recently, in addition to 5-methylcytosine …

DNA methylation is a typical epigenetic phenomenon. Numerous methods for detecting
global DNA methylation levels have been developed, among which LC-MS/MS has …

We developed and validated a rapid, sensitive, and specific liquid chromatography tandem
mass spectrometry (LC–MS/MS) method for determination of global DNA methylation in …

This work aimed to develop an ultrasensitive and specific immunosorbent assay for
simultaneous detection of double DNA methylation marks. Being considered the most …

Expression of genetic information is related to the presence of 5-methylcytosine in DNA. The
distribution of 5-methylcytosine varies in different tissues and its frequency is drastically …

The actual methods to evaluate total DNA methylation based on high performance liquid
chromatography (HPLC) are long and tedious due to the specific running buffers required. In …

The extent of the DNA methylation of genomic DNA as well as the methylation pattern of
many gene-regulatory areas are important aspects with regard to the state of genetic …

Global DNA methylation and hydroxymethylation play an important role in gene expression.
They can be connected with several diseases. The modification status could be a biomarker …