Epigenetics regulates gene expression and has been confirmed to play a critical role in a
variety of metabolic diseases, such as diabetes, obesity, non-alcoholic fatty liver disease …

In the next 10 years, one billion people are estimated to suffer from disabling consequences
of metabolic disorders, making them the number one noncommunicable disease on a global …

Epigenetic mechanisms control gene activity and the development of an organism. The
epigenome includes DNA methylation, histone modifications, and RNA-mediated processes …

Epigenetics is a molecular phenomenon that pertains to heritable changes in gene
expression that do not involve changes in the DNA sequence. Epigenetic modifications in a …

Epigenetics is a rapidly growing field of biology that studies the changes in gene expression
that are not due to alterations in the DNA sequence but rather the chemical modifications of …

Metabolic diseases, including type 2 diabetes mellitus (T2DM), are increasing worldwide at
an alarming rate. Epigenetic DNA modifications such as DNA methylation and histone …

Environmental factors (eg, malnutrition and physical inactivity) contribute largely to
metabolic disorders including obesity, type 2 diabetes, cardiometabolic disease and …

A long-term complication of obesity is the development of type 2 diabetes (T2D). Patients
with T2D have been described as having epigenetic modifications. Epigenetics is the post …

While epigenetic modifications of DNA and histones play main roles in gene transcription
regulation, recently discovered post-transcriptional RNA modifications, known as …

Background Obesity and type 2 diabetes (T2D) are major public health issues worldwide,
and put a significant burden on the healthcare system. Genetic variants, along with …