Epigenetic regulation in metabolic diseases: mechanisms and advances in clinical study
YL Wu, ZJ Lin, CC Li, X Lin, SK Shan, B Guo… - … and Targeted Therapy, 2023 - nature.com
Epigenetics regulates gene expression and has been confirmed to play a critical role in a
variety of metabolic diseases, such as diabetes, obesity, non-alcoholic fatty liver disease …
variety of metabolic diseases, such as diabetes, obesity, non-alcoholic fatty liver disease …
Epigenetics and metabolism in health and disease
E Tzika, T Dreker, A Imhof - Frontiers in genetics, 2018 - frontiersin.org
In the next 10 years, one billion people are estimated to suffer from disabling consequences
of metabolic disorders, making them the number one noncommunicable disease on a global …
of metabolic disorders, making them the number one noncommunicable disease on a global …
Epigenomes as therapeutic targets
CA Hamm, FF Costa - Pharmacology & Therapeutics, 2015 - Elsevier
Epigenetics is a molecular phenomenon that pertains to heritable changes in gene
expression that do not involve changes in the DNA sequence. Epigenetic modifications in a …
expression that do not involve changes in the DNA sequence. Epigenetic modifications in a …
[HTML][HTML] How epigenetics impacts on human diseases
A Farsetti, B Illi, C Gaetano - European journal of internal medicine, 2023 - Elsevier
Epigenetics is a rapidly growing field of biology that studies the changes in gene expression
that are not due to alterations in the DNA sequence but rather the chemical modifications of …
that are not due to alterations in the DNA sequence but rather the chemical modifications of …
Epigenetic flexibility in metabolic regulation: disease cause and prevention?
H Kirchner, ME Osler, A Krook, JR Zierath - Trends in cell biology, 2013 - cell.com
Metabolic diseases, including type 2 diabetes mellitus (T2DM), are increasing worldwide at
an alarming rate. Epigenetic DNA modifications such as DNA methylation and histone …
an alarming rate. Epigenetic DNA modifications such as DNA methylation and histone …
Epigenetic reprogramming in metabolic disorders: nutritional factors and beyond
Z Cheng, L Zheng, FA Almeida - The Journal of nutritional biochemistry, 2018 - Elsevier
Environmental factors (eg, malnutrition and physical inactivity) contribute largely to
metabolic disorders including obesity, type 2 diabetes, cardiometabolic disease and …
metabolic disorders including obesity, type 2 diabetes, cardiometabolic disease and …
Epigenetics in obesity and diabetes mellitus: new insights
R Suárez, SP Chapela, L Álvarez-Córdova… - Nutrients, 2023 - mdpi.com
A long-term complication of obesity is the development of type 2 diabetes (T2D). Patients
with T2D have been described as having epigenetic modifications. Epigenetics is the post …
with T2D have been described as having epigenetic modifications. Epigenetics is the post …
Epitranscriptomics in metabolic disease
Y Matsumura, FY Wei, J Sakai - Nature Metabolism, 2023 - nature.com
While epigenetic modifications of DNA and histones play main roles in gene transcription
regulation, recently discovered post-transcriptional RNA modifications, known as …
regulation, recently discovered post-transcriptional RNA modifications, known as …
[HTML][HTML] Epigenetic disturbances in obesity and diabetes: Epidemiological and functional insights
M Loh, L Zhou, HK Ng, JC Chambers - Molecular Metabolism, 2019 - Elsevier
Background Obesity and type 2 diabetes (T2D) are major public health issues worldwide,
and put a significant burden on the healthcare system. Genetic variants, along with …
and put a significant burden on the healthcare system. Genetic variants, along with …