Association between exposure to chemical mixtures and epigenetic ageing biomarkers: Modifying effects of thyroid hormones and physical activity
Evidence on the effects of internal chemical mixture exposures on biological age is limited. It
also remains unclear whether hormone homeostasis and lifestyle factors can modify such a …
also remains unclear whether hormone homeostasis and lifestyle factors can modify such a …
[HTML][HTML] Personal airborne chemical exposure and epigenetic ageing biomarkers in healthy Chinese elderly individuals: evidence from mixture approaches
Background Air pollution is associated with accelerated biological ages determined by DNA
methylation (DNAm) patterns, imposing further risks of age-related adverse effects …
methylation (DNAm) patterns, imposing further risks of age-related adverse effects …
Exposure to environmental pollutants and their association with biomarkers of aging: a multipollutant approach
A Vriens, TS Nawrot, BG Janssen… - Environmental …, 2019 - ACS Publications
Mitochondrial DNA (mtDNA) content and telomere length are putative aging biomarkers and
are sensitive to environmental stressors, including pollutants. Our objective was to identify …
are sensitive to environmental stressors, including pollutants. Our objective was to identify …
[HTML][HTML] The mixed effect of Endocrine-Disrupting chemicals on biological age Acceleration: Unveiling the mechanism and potential intervention target
W Huang, Z Zhang, M Colucci, L Deng, M Yang… - Environment …, 2024 - Elsevier
Introduction Although previous studies investigated the potential adverse effects of
endocrine-disrupting chemicals (EDCs) on biological age acceleration and aging-related …
endocrine-disrupting chemicals (EDCs) on biological age acceleration and aging-related …
Seasonal modification of the associations of exposure to polycyclic aromatic hydrocarbons or phthalates of cellular aging
J Hou, W Yin, P Li, C Hu, Y Zhang, X Wang… - Ecotoxicology and …, 2019 - Elsevier
Exposure to polycyclic aromatic hydrocarbons (PAHs) and phthalates link to oxidative stress
and inflammatory response, which exert cellular aging. However, modification effect of …
and inflammatory response, which exert cellular aging. However, modification effect of …
Associations between multiple metals exposure and biological aging: evidence from the Dongfeng-Tongji cohort
C Wang, S Hong, X Guan, Y Xiao, M Fu, H Meng… - Science of The Total …, 2023 - Elsevier
Aging is related to a progressive decline in physiological functions and is affected by
environmental factors. Metal exposures are linked with many health effects, but have poorly …
environmental factors. Metal exposures are linked with many health effects, but have poorly …
[HTML][HTML] Is this environment making you older? Molecular biomarkers and new approaches to investigate the influences of environmental chemicals through aging
Aging is characterized by a gradual and progressive decline in system integrity that occurs
with advancing chronological age. Although it is a physiological process, aging is …
with advancing chronological age. Although it is a physiological process, aging is …
[HTML][HTML] Does healthy lifestyle attenuate the detrimental effects of urinary polycyclic aromatic hydrocarbons on phenotypic aging? An analysis from NHANES 2001 …
Z Yang, F Pu, X Cao, X Li, S Sun, J Zhang… - Ecotoxicology and …, 2022 - Elsevier
Existing evidence has showed that exposure to polycyclic aromatic hydrocarbons (PAHs)
increases the risk of many chronic diseases. Given the close connection between aging (a …
increases the risk of many chronic diseases. Given the close connection between aging (a …
Association of air pollution with a urinary biomarker of biological aging and effect modification by vitamin K in the FLEMENGHO prospective population study
DS Martens, DW An, YL Yu, BS Chori… - Environmental …, 2023 - ehp.niehs.nih.gov
Background: A recently developed urinary peptidomics biological aging clock can be used
to study accelerated human aging. From 1990 to 2019, exposure to airborne particulate …
to study accelerated human aging. From 1990 to 2019, exposure to airborne particulate …
Association of PM2.5 Components with Acceleration of Aging: Moderating Role of Sex Hormones
R Pan, J Wang, W Chang, J Song, W Yi… - Environmental …, 2023 - ACS Publications
Fine particulate matter (PM2. 5) has been linked to aging risk, and a lack of knowledge
about the relationships between PM2. 5 components and aging risk impeded the …
about the relationships between PM2. 5 components and aging risk impeded the …
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- physical activity chemical mixtures
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- mixture approaches chemical exposure
- age acceleration mixed effect
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- seasonal modification associations of exposure