Association between exposure to chemical mixtures and epigenetic ageing biomarkers: Modifying effects of thyroid hormones and physical activity

W Shi, J Fang, H Ren, P Sun, J Liu, F Deng… - Journal of Hazardous …, 2024 - Elsevier
Evidence on the effects of internal chemical mixture exposures on biological age is limited. It
also remains unclear whether hormone homeostasis and lifestyle factors can modify such a …

[HTML][HTML] Personal airborne chemical exposure and epigenetic ageing biomarkers in healthy Chinese elderly individuals: evidence from mixture approaches

W Shi, X Gao, Y Cao, Y Chen, Q Cui, F Deng… - Environment …, 2022 - Elsevier
Background Air pollution is associated with accelerated biological ages determined by DNA
methylation (DNAm) patterns, imposing further risks of age-related adverse effects …

Exposure to environmental pollutants and their association with biomarkers of aging: a multipollutant approach

A Vriens, TS Nawrot, BG Janssen… - Environmental …, 2019 - ACS Publications
Mitochondrial DNA (mtDNA) content and telomere length are putative aging biomarkers and
are sensitive to environmental stressors, including pollutants. Our objective was to identify …

[HTML][HTML] The mixed effect of Endocrine-Disrupting chemicals on biological age Acceleration: Unveiling the mechanism and potential intervention target

W Huang, Z Zhang, M Colucci, L Deng, M Yang… - Environment …, 2024 - Elsevier
Introduction Although previous studies investigated the potential adverse effects of
endocrine-disrupting chemicals (EDCs) on biological age acceleration and aging-related …

Seasonal modification of the associations of exposure to polycyclic aromatic hydrocarbons or phthalates of cellular aging

J Hou, W Yin, P Li, C Hu, Y Zhang, X Wang… - Ecotoxicology and …, 2019 - Elsevier
Exposure to polycyclic aromatic hydrocarbons (PAHs) and phthalates link to oxidative stress
and inflammatory response, which exert cellular aging. However, modification effect of …

Associations between multiple metals exposure and biological aging: evidence from the Dongfeng-Tongji cohort

C Wang, S Hong, X Guan, Y Xiao, M Fu, H Meng… - Science of The Total …, 2023 - Elsevier
Aging is related to a progressive decline in physiological functions and is affected by
environmental factors. Metal exposures are linked with many health effects, but have poorly …

[HTML][HTML] Is this environment making you older? Molecular biomarkers and new approaches to investigate the influences of environmental chemicals through aging

D Prada, D Belsky, AA Baccarelli - La Medicina del Lavoro, 2021 - ncbi.nlm.nih.gov
Aging is characterized by a gradual and progressive decline in system integrity that occurs
with advancing chronological age. Although it is a physiological process, aging is …

[HTML][HTML] Does healthy lifestyle attenuate the detrimental effects of urinary polycyclic aromatic hydrocarbons on phenotypic aging? An analysis from NHANES 2001 …

Z Yang, F Pu, X Cao, X Li, S Sun, J Zhang… - Ecotoxicology and …, 2022 - Elsevier
Existing evidence has showed that exposure to polycyclic aromatic hydrocarbons (PAHs)
increases the risk of many chronic diseases. Given the close connection between aging (a …

Association of air pollution with a urinary biomarker of biological aging and effect modification by vitamin K in the FLEMENGHO prospective population study

DS Martens, DW An, YL Yu, BS Chori… - Environmental …, 2023 - ehp.niehs.nih.gov
Background: A recently developed urinary peptidomics biological aging clock can be used
to study accelerated human aging. From 1990 to 2019, exposure to airborne particulate …

Association of PM2.5 Components with Acceleration of Aging: Moderating Role of Sex Hormones

R Pan, J Wang, W Chang, J Song, W Yi… - Environmental …, 2023 - ACS Publications
Fine particulate matter (PM2. 5) has been linked to aging risk, and a lack of knowledge
about the relationships between PM2. 5 components and aging risk impeded the …