[HTML][HTML] MicroRNA-19b-3p dysfunction of mesenchymal stem cell-derived exosomes from patients with abdominal aortic aneurysm impairs therapeutic efficacy

Y Zhang, X Huang, T Sun, L Shi, B Liu, Y Hong… - Journal of …, 2023 - Springer
Senescence of vascular smooth muscle cells (VSMCs) contributes to the formation of
abdominal aortic aneurysm (AAA). Although mesenchymal stem cell exosomes (MSC-EXO) …

Alternative therapeutic strategy for existing aortic aneurysms using mesenchymal stem cell–derived exosomes

M Kozakai, Y Narita, A Yamawaki-Ogata… - Expert Opinion on …, 2022 - Taylor & Francis
Background Several studies demonstrated the therapeutic potential of mesenchymal stem
cell–derived exosomes (MSC-exs) based on their anti-inflammatory properties. The …

[HTML][HTML] MicroRNA-29a-3p delivery via exosomes derived from engineered human mesenchymal stem cells exerts tumour suppressive effects by inhibiting migration …

Z Zhang, X Guo, X Guo, R Yu, M Qian, S Wang… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Vasculogenic mimicry (VM), the formation of an alternative microvascular circulation
independent of VEGF-driven angiogenesis, is reluctant to anti-angiogenesis therapy for …

[HTML][HTML] Exosomal miR-17-5p from adipose-derived mesenchymal stem cells inhibits abdominal aortic aneurysm by suppressing TXNIP-NLRP3 inflammasome

J Hu, Y Jiang, X Wu, Z Wu, J Qin, Z Zhao, B Li… - Stem Cell Research & …, 2022 - Springer
Background Preclinical studies have suggested that adipose-derived mesenchymal stem
cells (ADSCs) transplantation can suppress abdominal aortic inflammation and aneurysm …

[HTML][HTML] Mesenchymal stem-cell-derived exosomal miR-145 inhibits atherosclerosis by targeting JAM-A

W Yang, R Yin, X Zhu, S Yang, J Wang, Z Zhou… - … Therapy-Nucleic Acids, 2021 - cell.com
Atherosclerosis is a chronic inflammatory disease associated with the development of
plaques that can be converted into an acute clinical event by thrombosis or plaque rupture …

[HTML][HTML] Adipose-derived mesenchymal stem cells-derived exosome-mediated microRNA-342-5p protects endothelial cells against atherosclerosis

X Xing, Z Li, X Yang, M Li, C Liu, Y Pang… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Exosomes are reported to mediate several disease-related microRNAs (miRNAs) to affect
the progression of diseases, including atherosclerosis. Here, we aimed to screen the …

Mesenchymal stem cells-derived exosomes modulate vascular endothelial injury via miR-144-5p/PTEN in intracranial aneurysm

G Yang, H Qin, B Liu, X Zhao, H Yin - Human Cell, 2021 - Springer
Phosphatase and tensin homolog (PTEN) is known to be involved in the pathogenesis of
intracranial aneurysm (IA). This study investigated the molecular mechanism of exosomal …

microRNA‐16‐5p‐containing exosomes derived from bone marrow‐derived mesenchymal stem cells inhibit proliferation, migration, and invasion, while promoting …

Y Xu, L Shen, F Li, J Yang, X Wan… - Journal of cellular …, 2019 - Wiley Online Library
Colorectal cancer (CRC) is a form of cancer developing from either the colon or rectum.
Nowadays, research supports the functionality of exosome expressing microRNAs (miRNAs) …

Adipose‐Derived Mesenchymal Stem Cells Isolated from Patients with Abdominal Aortic Aneurysm Exhibit Senescence Phenomena

X Huang, H Zhang, X Liang, Y Hong… - Oxidative Medicine …, 2019 - Wiley Online Library
Mesenchymal stem cells (MSCs) have shown beneficial effects in the treatment of
abdominal aortic aneurysm (AAA). Nonetheless, the biological properties of adipose …

[HTML][HTML] Hydrogen peroxide-induced senescence reduces the wound healing-promoting effects of mesenchymal stem cell-derived exosomes partially via miR-146a

M Xu, X Su, X Xiao, H Yu, X Li, A Keating… - Aging and …, 2021 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) have beneficial effects on wound healing. MSCs function
through direct cell-cell communication or indirectly through paracrine secretion of exosomes …