Air pollution and human endogenous retrovirus methylation in the school inner-city asthma intervention study
Human endogenous retroviruses (HERVs) are transposable genomic elements generally
repressed through DNA methylation. HERVs can be demethylated and expressed in …
repressed through DNA methylation. HERVs can be demethylated and expressed in …
DNA methylation levels associated with race and childhood asthma severity
MA Chan, CE Ciaccio, NM Gigliotti… - Journal of …, 2017 - Taylor & Francis
Objective: Asthma is a common chronic childhood disease worldwide. Socioeconomic
status, genetic predisposition and environmental factors contribute to its incidence and …
status, genetic predisposition and environmental factors contribute to its incidence and …
[HTML][HTML] Rhinovirus infections change DNA methylation and mRNA expression in children with asthma
Human rhinovirus infection (HRVI) plays an important role in asthma exacerbations and is
thought to be involved in asthma development during early childhood. We hypothesized that …
thought to be involved in asthma development during early childhood. We hypothesized that …
DNA methylation and childhood asthma in the inner city
IV Yang, BS Pedersen, A Liu, GT O'Connor… - Journal of Allergy and …, 2015 - Elsevier
Background Epigenetic marks are heritable, influenced by the environment, direct the
maturation of T lymphocytes, and in mice enhance the development of allergic airway …
maturation of T lymphocytes, and in mice enhance the development of allergic airway …
[HTML][HTML] Epigenome-wide association study of DNA methylation and adult asthma in the Agricultural Lung Health Study
Epigenome-wide studies of methylation in children support a role for epigenetic
mechanisms in asthma; however, studies in adults are rare and few have examined non …
mechanisms in asthma; however, studies in adults are rare and few have examined non …
Farm exposure and time trends in early childhood may influence DNA methylation in genes related to asthma and allergy
S Michel, F Busato, J Genuneit, J Pekkanen… - Allergy, 2013 - Wiley Online Library
Background Genetic susceptibility and environmental influences are important contributors
to the development of asthma and atopic diseases. Epigenetic mechanisms may facilitate …
to the development of asthma and atopic diseases. Epigenetic mechanisms may facilitate …
Rapid DNA methylation changes after exposure to traffic particles
A Baccarelli, RO Wright, V Bollati… - American journal of …, 2009 - atsjournals.org
Rationale: Exposure to particulate air pollution has been related to increased hospitalization
and death, particularly from cardiovascular disease. Lower blood DNA methylation content …
and death, particularly from cardiovascular disease. Lower blood DNA methylation content …
Infant RSV immunoprophylaxis changes nasal epithelial DNA methylation at 6 years of age
Background Respiratory syncytial virus (RSV) infection has been associated with childhood
wheeze and asthma, and potential mechanisms include persistent epigenetic effects …
wheeze and asthma, and potential mechanisms include persistent epigenetic effects …
An environmental epigenetic study of ADRB2 5′‐UTR methylation and childhood asthma severity
A Fu, BP Leaderer, JF Gent… - … & Experimental Allergy, 2012 - Wiley Online Library
Background Beta‐2 adrenergic receptor (ADRB 2) is the primary target of both short‐and
long‐acting beta‐agonist asthma medications. ADRB 2 5′‐UTR methylation changes in …
long‐acting beta‐agonist asthma medications. ADRB 2 5′‐UTR methylation changes in …
[HTML][HTML] Dietary intake is associated with respiratory health outcomes and DNA methylation in children with asthma
Background Asthma is an increasingly common chronic disease among children, and data
point toward a complex mechanism involving genetic, environmental and epigenetic factors …
point toward a complex mechanism involving genetic, environmental and epigenetic factors …