Antimicrobial resistance has become a significant public health problem globally with
multidrug resistant Gram negative (MDR-GN) bacteria being the main representatives. The …

(1) Background: Infections caused by multidrug-resistant (MDR) or extensively drug-resistant
(XDR) bacteria represent a challenge in the neonatal population due to disease severity and …

Making further progress in reducing child mortality hinges on lowering the annual count of
neonatal deaths; currently, this stands at 2.5 million, 23% of which are the direct result of …

Infants admitted to the neonatal intensive care unit, particularly those born preterm, are at
high risk for infection due to the combination of an immature immune system, prolonged …

Background: Currently, the escalation of microbial resistance poses a significant global
challenge. Children are more susceptible to develop infections and therefore are prescribed …

Neonatal sepsis causes up to an estimated 680,000 deaths annually worldwide,
predominantly in low-and middle-income countries (LMICs). A significant and growing …

Despite a significant decline in deaths in children younger than 5 years globally in the past
three decades, preventable and treatable infectious diseases remain the leading cause of …

Rational medicine use in neonates implies the prescription and administration of age-
appropriate drug formulations, selecting the most efficacious and safe dose, all based on …

Background: Infections by multi-drug-resistant (MDR) organisms are sharply increasing in
newborns worldwide. In low and middle-income countries, a disproportionate amount of …

New initiatives have been introduced in Europe and the USA to encourage more rapid
development of antibiotics. The need to ensure these new antibiotics can be safely used in …