Identifying genetic variants that are associated with variation in DNA methylation, an
analysis commonly referred to as methylation quantitative trait locus (meQTL) mapping, is an …

DNA methylation is an important epigenetic regulator of gene expression. Recent studies
have revealed widespread associations between genetic variation and methylation levels …

Multiple recent studies highlight that genetic variants can have strong impacts on a
significant proportion of the human DNA methylome. Methylation quantitative trait loci, or …

Identifying methylation quantitative trait loci (meQTLs) and integrating them with disease-
associated variants from genome-wide association studies (GWAS) may illuminate …

Studies of DNA methylation (DNAm) in solid human tissues are relatively scarce; tissue-
specific characterization of DNAm is needed to understand its role in gene regulation and its …

Background Individual genotypes at specific loci can result in different patterns of DNA
methylation. These methylation quantitative trait loci (meQTLs) influence methylation across …

Background Genetic influence on DNA methylation is potentially an important mechanism
affecting individual differences in humans. We use next-generation sequencing to assay …

Traditionally, DNA methylation has been thought of as being involved in gene silencing, but
work in recent years has shown a more complex picture, and the relationship between DNA …

DNA methylation may contribute to the etiology of complex genetic disorders through its
impact on genome integrity and gene expression; it is modulated by DNA-sequence …

Here we report three epigenome-wide association studies (EWAS) of DNA methylation on
self-reported race, global genetic ancestry, and local genetic ancestry in admixed Americans …