Pan-cancer analysis of SLC2A family genes as prognostic biomarkers and therapeutic targets

Y Liu, X Li, J Yang, S Chen, C Zhu, Y Shi, S Dang… - Heliyon, 2024 - cell.com
Background The major facilitator superfamily glucose transporters (GLUTs), encoded by
solute carrier 2A (SLC2A) genes, mediate the transmembrane movement and uptake of …

SLC2As as diagnostic markers and therapeutic targets in LUAD patients through bioinformatic analysis

Y Zhang, H Qin, J Bian, Z Ma, H Yi - Frontiers in Pharmacology, 2022 - frontiersin.org
Facilitative glucose transporters (GLUTs), which are encoded by solute carrier 2A (SLC2A)
genes, are responsible for mediating glucose absorption. In order to meet their higher …

The prognostic and clinicopathological significance of SLC7A11 in human cancers: a systematic review and meta-analysis

J Wang, S Hao, G Song, Y Wang, Q Hao - PeerJ, 2023 - peerj.com
Objective It is of great importance to recognize bio-markers for cancer prognosis. However,
the association between solute carrier family 7 member 11 (SLC7A11) and prognosis is still …

[HTML][HTML] A pan-cancer analysis of SLC1A5 in human cancers

J Ni, W Dai, C Liu, Y Ling, H Mou - Heliyon, 2023 - cell.com
Background The alanine-serine-cysteine transporter 2, ASCT2 (solute carrier family 1
member 5, SLC1A5), is a major transporter of the amino acid, glutamine. Although SLC1A5 …

Systematic pan-cancer analysis identifies SLC31A1 as a biomarker in multiple tumor types

FS Kong, CY Ren, R Jia, Y Zhou, JH Chen, Y Ma - BMC medical genomics, 2023 - Springer
Abstract Background Solute Carrier Family 31 Member 1 (SLC31A1) has recently been
identified as a cuproptosis-regulatory gene. Recent studies have indicated that SLC31A1 …

[HTML][HTML] SLC2A2 (GLUT2) as a novel prognostic factor for hepatocellular carcinoma

YH Kim, DC Jeong, K Pak, ME Han, JY Kim… - Oncotarget, 2017 - ncbi.nlm.nih.gov
High rates of glucose transport via solute carrier (SLC2A, GLUT) family members are
required to satisfy the high metabolic demands of cancer cells, and because of this …

Integrated analysis of Solute carrier family-2 members reveals SLC2A4 as an independent favorable prognostic biomarker for breast cancer

Z Shi, J Liu, F Wang, Y Li - Channels, 2021 - Taylor & Francis
Most of Solute carrier family-2 (SLC2) members play a key role of facilitative transporters,
and glucose transporter (GLUT) proteins encoded by SLC2s can transport hexoses or …

Correlation Between Prognostic Biomarker SLC1A5 and Immune Infiltrates in Various Types of Cancers Including Hepatocellular Carcinoma

J Zhao, Z Yang, M Tu, W Meng, H Gao, MD Li… - Frontiers in …, 2021 - frontiersin.org
Background Solute carrier family 1 member 5 (SLC1A5) is a major glutamine transporter
and plays a key role in tumor growth. The main objectives of this study were to visualize the …

Comprehensive molecular and clinical characterization of SLC1A5 in human cancers

H Zhang, K Cui, S Yao, Y Yin, D Liu, Z Huang - Pathology-Research and …, 2021 - Elsevier
Although SLC1A5 has been reported to be closely associated with some cancer types, a
comprehensive and systematic assessment of SLC1A5 across human cancers is lacking …

[HTML][HTML] Comprehensive analysis of pan-cancer reveals the potential of SLC16A1 as a prognostic and immunological biomarker

L Chen, Y Li, X Deng - Medicine, 2023 - journals.lww.com
SLC16A1 plays an important role in the development of multiple cancer types. Pan-cancer
analysis may have significant impacts on the exploration of the relationship between …