With over 220,000 cases and 180,000 deaths annually, Cryptococcus neoformans is the
most common cause of fungal meningitis and a leading cause of death in HIV/AIDS patients …

Cryptococcal meningitis is the most common cause of meningitis among HIV/AIDS patients
in sub-Saharan Africa, and worldwide causes over 223,000 cases leading to more than …

Cryptococcus neoformans is an opportunistic fungal pathogen that causes over 180,000
annual deaths in HIV/AIDS patients. Innate phagocytes in the lungs, such as dendritic cells …

Many aspects of the host response to invasive cryptococcal infections remain poorly
understood. In order to explore the pathobiology of infection with common clinical strains, we …

The fungal pathogen Cryptococcus neoformans can cause life-threatening infections in
immune compromised individuals. This pathogen is typically acquired via inhalation, and …

Experimental pulmonary Cryptococcus neoformans infection in BALB/c mice is associated
with polarized Th2-type cytokine production, alternative macrophage activation, and severe …

Clearance of pulmonary infection with the fungal pathogen Cryptococcus neoformans is
associated with the accumulation and activation of lung macrophages. However, the …

Cryptococcal infections are primarily caused by two related fungal species: Cryptococcus
neoformans and Cryptococcus gattii. It is well known that C. neoformans generally affects …

Alternative macrophage activation is associated with exacerbated disease in murine models
of pulmonary cryptococcosis. The present study evaluated the efficacy of interferon-γ …

Background Cryptococcus neoformans (C. neoformans) is a globally distributed fungal
pathogen with the potential to cause serious disease, particularly among immune …