Transcription, translation and subsequent protein modification represent the transfer of
genetic information from the archival copy of DNA to the short-lived messenger RNA, usually …

In the first half of the twentieth century, developmental biology and genetics were separate
disciplines. The word epigenetics was coined by Waddington to link the two fields …

Classical genetics has revealed the mechanisms for the transmission of genes from
generation to generation, but the strategy of the genes in unfolding the developmental …

Different definitions of epigenetics are discussed and the following definition is suggested:
the study of the changes in gene expression, which occur in organisms with differentiated …

The above experiments support a relatively simple model to explain the role of DNA
methylation in vivo. Most tissue-specific genes are methylated. The methyl groups may …

Genes are essential for the transmission of genetic information from generation to
generation, and this mechanism of inheritance is fully understood. Genes are also essential …

DNA methylation is commonly associated with gene silencing, and a link between histone
deacetylation and DNA methylation has been established. However, the transcriptional …

Cells of a multicellular organism are genetically homogeneous but structurally and
functionally heterogeneous owing to the differential expression of genes. Many of these …

I have tried to unpack the polysemy of the word epigenetics by adopting a historical point of
view and by focusing on the models that were proposed at the beginning of the 1960s to …

Although the field of genetics has grown by leaps and bounds within the last decade due to
the completion and availability of the human genome sequence, transcriptional regulation …