[HTML][HTML] Silencing and transcriptional regulation of endogenous retroviruses: an overview
FK Geis, SP Goff - Viruses, 2020 - mdpi.com
Almost half of the human genome is made up of transposable elements (TEs), and about 8%
consists of endogenous retroviruses (ERVs). ERVs are remnants of ancient exogenous …
consists of endogenous retroviruses (ERVs). ERVs are remnants of ancient exogenous …
Endogenous retroviruses and the development of cancer
G Kassiotis - The Journal of Immunology, 2014 - journals.aai.org
Mammalian genomes include a considerable number of endogenous retroviruses (ERVs),
relics of ancestral infectious retroviruses, whose proviruses have invaded the germ-line. The …
relics of ancestral infectious retroviruses, whose proviruses have invaded the germ-line. The …
[HTML][HTML] Endogenous retroviruses in the origins and treatment of cancer
N Jansz, GJ Faulkner - Genome biology, 2021 - Springer
Endogenous retroviruses (ERVs) are emerging as promising therapeutic targets in cancer.
As remnants of ancient retroviral infections, ERV-derived regulatory elements coordinate …
As remnants of ancient retroviral infections, ERV-derived regulatory elements coordinate …
[HTML][HTML] Epigenetic control of human endogenous retrovirus expression: focus on regulation of long-terminal repeats (LTRs)
TP Hurst, G Magiorkinis - Viruses, 2017 - mdpi.com
Transposable elements, including endogenous retroviruses (ERVs), comprise almost 45%
of the human genome. This could represent a significant pathogenic burden but it is …
of the human genome. This could represent a significant pathogenic burden but it is …
[HTML][HTML] Human endogenous retroviruses in cancer: Expression, regulation and function
Y Gao, XF Yu, T Chen - Oncology Letters, 2021 - spandidos-publications.com
Human endogenous retroviruses (HERVs) are the remnants of ancient retroviruses that
infected human germline cells and became integrated into the human genome millions of …
infected human germline cells and became integrated into the human genome millions of …
[HTML][HTML] Endogenous retroviral promoter exaptation in human cancer
Cancer arises from a series of genetic and epigenetic changes, which result in abnormal
expression or mutational activation of oncogenes, as well as suppression/inactivation of …
expression or mutational activation of oncogenes, as well as suppression/inactivation of …
[HTML][HTML] Human endogenous retroviruses (HERVs): shaping the innate immune response in cancers
V Alcazer, P Bonaventura, S Depil - Cancers, 2020 - mdpi.com
Human Endogenous Retroviruses (HERVs) are accounting for 8% of the human genome.
These sequences are remnants from ancient germline infections by exogenous retroviruses …
These sequences are remnants from ancient germline infections by exogenous retroviruses …
[HTML][HTML] Endogenous retroviruses as modulators of innate immunity
E Russ, S Iordanskiy - Pathogens, 2023 - mdpi.com
Endogenous retroviruses (ERVs), or LTR retrotransposons, are a class of transposable
elements that are highly represented in mammalian genomes. Human ERVs (HERVs) make …
elements that are highly represented in mammalian genomes. Human ERVs (HERVs) make …
Expressional activation and functional roles of human endogenous retroviruses in cancers
M Zhang, JQ Liang, S Zheng - Reviews in medical virology, 2019 - Wiley Online Library
Human endogenous retroviruses (HERVs) are widely believed to be remnants of ancestral
germ line infections by exogenous retroviruses. Although HERVs are deemed as …
germ line infections by exogenous retroviruses. Although HERVs are deemed as …
[HTML][HTML] Endogenous retroviruses: with us and against us
TJ Meyer, JL Rosenkrantz, L Carbone… - Frontiers in …, 2017 - frontiersin.org
Mammalian genomes are scattered with thousands of copies of endogenous retroviruses
(ERVs), mobile genetic elements that are relics of ancient retroviral infections. After inserting …
(ERVs), mobile genetic elements that are relics of ancient retroviral infections. After inserting …