Therapeutic potential of glucagon-like peptide-1 agonists in polycystic ovary syndrome: from current clinical evidence to future perspectives

M Jensterle, R Herman, A Janež - Biomedicines, 2022 - mdpi.com
Despite the continuous effort to understand the pathophysiology and determine potential
therapeutic targets, PCOS treatment largely depends on lifestyle intervention and …

Do GLP-1 Analogs Have a Place in the Treatment of PCOS? New Insights and Promising Therapies

A Szczesnowicz, A Szeliga, O Niwczyk, G Bala… - Journal of Clinical …, 2023 - mdpi.com
Polycystic ovary syndrome (PCOS) is the most prevalent endocrinopathy in women of
reproductive age. This condition is characterized by hyperandrogenism and either oligo-or …

The antiobesity effect of GLP‐1 receptor agonists alone or in combination with metformin in overweight/obese women with polycystic ovary syndrome: a systematic …

X Lyu, T Lyu, X Wang, H Zhu, H Pan… - International journal …, 2021 - Wiley Online Library
Objectives. Both glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and metformin
(MET) have markedly antiobesity effects in overweight/obese polycystic ovary syndrome …

The therapeutic effects of glucagon-like peptide-1 receptor agonists and metformin on polycystic ovary syndrome: A protocol for systematic review and meta-analysis

R Ma, X Ding, Y Wang, Y Deng, A Sun - Medicine, 2021 - journals.lww.com
Background: Obesity and insulin resistance (IR) are common in polycystic ovary syndrome
(PCOS), which contribute to reproductive and metabolic abnormalities. Metformin increases …

GLP-1 receptor agonists in the treatment of polycystic ovary syndrome

EM Lamos, R Malek, SN Davis - Expert Review of Clinical …, 2017 - Taylor & Francis
Introduction: Polycystic ovarian syndrome (PCOS) affects many women of child-bearing age
and is characterized by hyperandrogenism, ovulatory and metabolic dysfunction. A primary …

Glucagon-like peptide-1 (GLP-1) receptor agonists in the treatment of obese women with polycystic ovary syndrome

T Tzotzas, SN Karras, N Katsiki - Current vascular …, 2017 - ingentaconnect.com
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in females and
is often associated with a number of cardiometabolic disorders such as central obesity …

[HTML][HTML] GLP-1 receptor agonists, polycystic ovary syndrome and reproductive dysfunction: Current research and future horizons

GS Papaetis, A Kyriacou - Advances in Clinical and …, 2022 - advances.umw.edu.pl
Polycystic ovary syndrome (PCOS) is a disorder that involves several organ systems and
cellular pathways. It is strongly influenced by environmental and epigenetic factors. The …

GLP-1 receptor agonists versus metformin in PCOS: a systematic review and meta-analysis

Y Han, Y Li, B He - Reproductive biomedicine online, 2019 - Elsevier
This meta-analysis aimed to evaluate the efficacy and safety of glucagon-like peptide 1 (GLP-
1) receptor agonists for women with polycystic ovary syndrome (PCOS) by comparing their …

The potential role of incretin-based therapies for polycystic ovary syndrome: a narrative review of the current evidence

MA Abdalla, H Deshmukh, S Atkin… - … in endocrinology and …, 2021 - journals.sagepub.com
Introduction: Polycystic ovary syndrome (PCOS) is a common endocrine disorder that affects
women of reproductive age. Metabolic consequences associated with PCOS include, but …

A systematic review of GLP-1 agonists on the metabolic syndrome in women with polycystic ovaries

M Niafar, L Pourafkari, J Porhomayon… - Archives of Gynecology …, 2016 - Springer
Purpose Glucagon-like peptides receptor agonists are currently approved as anti-obesity
agents, yet the experience with their use in polycystic ovarian syndromes (PCOS)-related …