Mitochondria are organelles responsible for several functions involved in cellular balance,
including energy generation and apoptosis. For decades now, it has been well-known that …

Mitochondria are the energy production center in cells, which regulate aerobic metabolism,
calcium balance, gene expression and cell death. Their homeostasis is crucial for cell …

The regulation of mitochondrial proteome is unique in that its components have origins in
both mitochondria and nucleus. With the development of OMICS technologies, emerging …

The bidirectional cross talk between nuclear and mitochondrial DNA is essential for cellular
homeostasis and proper functioning. Mitochondria depend on nuclear contribution for much …

Mitochondria are peculiar organelles whose proper function depends on the crosstalk
between two genomes, mitochondrial and nuclear. The human mitochondrial genome …

Epigenetic modifications of the nuclear genome have been well studied and it is established
that these modifications play a key role in nuclear gene expression. However, the status of …

Mitochondria are the main hubs for cellular energy production. Metabolites produced in
mitochondria not only feed many important biosynthesis pathways but also function as …

Mitochondrial epitranscriptomics refers to the modifications occurring in all the different RNA
types of mitochondria. Although the number of mitochondrial RNA modifications is less than …

Mitochondria are maternally inherited semi-autonomous organelles that play a central role
in redox balance, energy metabolism, control of integrated stress responses, and cellular …

The rate/quality of human aging and the development/progression of diseases depend on a
complex interplay among genetics, epigenetics and environment. In this scenario …