How vascular smooth muscle cell phenotype switching contributes to vascular disease
G Cao, X Xuan, J Hu, R Zhang, H Jin… - Cell Communication and …, 2022 - Springer
Vascular smooth muscle cells (VSMCs) are the most abundant cell in vessels. Earlier
experiments have found that VSMCs possess high plasticity. Vascular injury stimulates …
experiments have found that VSMCs possess high plasticity. Vascular injury stimulates …
Role of vascular smooth muscle cell phenotype switching in arteriogenesis
JV Ashraf, A Al Haj Zen - International journal of molecular sciences, 2021 - mdpi.com
Arteriogenesis is one of the primary physiological means by which the circulatory collateral
system restores blood flow after significant arterial occlusion in peripheral arterial disease …
system restores blood flow after significant arterial occlusion in peripheral arterial disease …
Smooth muscle cell-driven vascular diseases and molecular mechanisms of VSMC plasticity
A Frismantiene, M Philippova, P Erne, TJ Resink - Cellular signalling, 2018 - Elsevier
Vascular smooth muscle cells (VSMCs) are the major cell type in blood vessels. Unlike
many other mature cell types in the adult body, VSMC do not terminally differentiate but …
many other mature cell types in the adult body, VSMC do not terminally differentiate but …
Vascular smooth muscle cells phenotypic switching in cardiovascular diseases
HY Tang, AQ Chen, H Zhang, XF Gao, XQ Kong… - Cells, 2022 - mdpi.com
Vascular smooth muscle cells (VSMCs), the major cell type in the arterial vessel wall, have a
contractile phenotype that maintains the normal vessel structure and function under …
contractile phenotype that maintains the normal vessel structure and function under …
[HTML][HTML] Targeting smooth muscle cell phenotypic switching in vascular disease
Objective The phenotypic plasticity of vascular smooth muscle cells (VSMCs) is central to
vessel growth and remodeling, but also contributes to cardiovascular pathologies. New …
vessel growth and remodeling, but also contributes to cardiovascular pathologies. New …
An update on the phenotypic switching of vascular smooth muscle cells in the pathogenesis of atherosclerosis
F Zhang, X Guo, Y Xia, L Mao - Cellular and Molecular Life Sciences, 2022 - Springer
Vascular smooth muscle cells (VSMCs) are involved in phenotypic switching in
atherosclerosis. This switching is characterized by VSMC dedifferentiation, migration, and …
atherosclerosis. This switching is characterized by VSMC dedifferentiation, migration, and …
Mechanisms of vascular smooth muscle cell investment and phenotypic diversification in vascular diseases
MD Worssam, HF Jørgensen - Biochemical Society Transactions, 2021 - portlandpress.com
In contrast with the heart, the adult mammalian vasculature retains significant remodelling
capacity, dysregulation of which is implicated in disease development. In particular, vascular …
capacity, dysregulation of which is implicated in disease development. In particular, vascular …
An overview of potential molecular mechanisms involved in VSMC phenotypic modulation
MJ Zhang, Y Zhou, L Chen, YQ Wang, X Wang… - Histochemistry and cell …, 2016 - Springer
The fully differentiated medial vascular smooth muscle cells (VSMCs) of mature vessels
keep quiescent and contractile. However, VSMC can exhibit the plasticity in phenotype …
keep quiescent and contractile. However, VSMC can exhibit the plasticity in phenotype …
[HTML][HTML] Regulation of vascular smooth muscle cell differentiation
EM Rzucidlo, KA Martin, RJ Powell - Journal of vascular surgery, 2007 - Elsevier
Vascular smooth muscle cell (VSMC) differentiation is an essential component of vascular
development. These cells perform biosynthetic, proliferative, and contractile roles in the …
development. These cells perform biosynthetic, proliferative, and contractile roles in the …
Fate and state of vascular smooth muscle cells in atherosclerosis
Vascular smooth muscle cells (VSMCs) have long been associated with phenotypic
modulation/plasticity or dedifferentiation. Innovative technologies in cell lineage tracing …
modulation/plasticity or dedifferentiation. Innovative technologies in cell lineage tracing …