Brain tumors are a group of heterogeneous diseases arising from abnormally proliferating
cells that can negatively impact the eloquent function of this organ. Drug therapies have …

Brain drug delivery is a major challenge for therapy of central nervous system (CNS)
diseases. Biochemical modifications of drugs or drug nanocarriers, methods of local …

The presence of blood–brain barrier (BBB) and/or blood–brain–tumor barriers (BBTB) is one
of the main obstacles to effectively deliver therapeutics to our central nervous system (CNS); …

For a chemotherapeutic agent to be effective, it must conquer the presence of blood–brain
barrier (BBB), which limits the penetration of drugs into the brain. Tumours in the brain …

The presence of blood–brain barrier (BBB) and/or blood–brain–tumor barriers (BBTB) is one
of the main obstacles to effectively deliver therapeutics to our central nervous system (CNS); …

Even though the last decade has seen a surge in the identification of molecular targets and
targeted therapies in pediatric brain tumors, the blood brain barrier (BBB) remains a …

Brain tumors are particularly challenging malignancies, due to their location in a structurally
and functionally distinct part of the human body–the central nervous system (CNS). The CNS …

Simple Summary Advancements in understanding the blood–brain barrier (BBB) and blood–
tumor barrier (BTB) structures emphasize the need to explore functional differences …

Glioblastoma multiforme (GBM) diffusely infiltrates normal brain tissue. The presence of the
blood‐brain barrier (BBB) poses difficulties for targeted delivery of currently available …

Existing drug delivery methods have not led to a significant increase in survival for patients
with malignant primary brain tumors. While the combination of conventional therapies …