Epigenetic mechanisms in schizophrenia and other psychotic disorders: a systematic review of empirical human findings

L Smigielski, V Jagannath, W Rössler, S Walitza… - Molecular …, 2020 - nature.com
Schizophrenia and other psychotic disorders are highly debilitating psychiatric conditions
that lack a clear etiology and exhibit polygenic inheritance underlain by pleiotropic genes …

Epigenetic modifications in schizophrenia and related disorders: molecular scars of environmental exposures and source of phenotypic variability

J Richetto, U Meyer - Biological Psychiatry, 2021 - Elsevier
Epigenetic modifications are increasingly recognized to play a role in the etiology and
pathophysiology of schizophrenia and other psychiatric disorders with developmental …

Epigenetic studies of schizophrenia: progress, predicaments, and promises for the future

E Dempster, J Viana, R Pidsley, J Mill - Schizophrenia bulletin, 2013 - academic.oup.com
Increased understanding about the functional complexity of the genome has led to growing
recognition about the role of epigenetic variation in the etiology of schizophrenia. Epigenetic …

Epigenomic dysregulation in schizophrenia: in search of disease etiology and biomarkers

B Khavari, MJ Cairns - Cells, 2020 - mdpi.com
Schizophrenia is a severe psychiatric disorder with a complex array of signs and symptoms
that causes very significant disability in young people. While schizophrenia has a strong …

Epigenetic mechanisms in schizophrenia

S Akbarian - Dialogues in clinical neuroscience, 2014 - Taylor & Francis
Schizophrenia is a major psychiatric disorder that lacks a unifying neuropathology, while
currently available pharmacological treatments provide only limited benefits to many …

DNA methylation in schizophrenia: progress and challenges of epigenetic studies

M Nishioka, M Bundo, K Kasai, K Iwamoto - Genome medicine, 2012 - Springer
Schizophrenia is a severe psychiatric disease affecting about 1% of the world's population,
with significant effects on patients and society. Genetic studies have identified several …

Genome‐Wide Findings in Schizophrenia and the Role of Gene–Environment Interplay

R Van Winkel, G Esquivel, G Kenis… - CNS neuroscience & …, 2010 - Wiley Online Library
The recent advent of genome‐wide mass‐marker technology has resulted in renewed
optimism to unravel the genetic architecture of psychotic disorders. Genome‐wide …

Epigenetic mediation of environmental influences in major psychotic disorders

BPF Rutten, J Mill - Schizophrenia bulletin, 2009 - academic.oup.com
The major psychotic disorders schizophrenia and bipolar disorder are etiologically complex
involving both heritable and nonheritable factors. The absence of consistently replicated …

An update on the epigenetics of psychotic diseases and autism

HM Abdolmaleky, JR Zhou, S Thiagalingam - Epigenomics, 2015 - Future Medicine
The examination of potential roles of epigenetic alterations in the pathogenesis of psychotic
diseases have become an essential alternative in recent years as genetic studies alone are …

Epigenetics of schizophrenia

A Srivastava, O Dada, J Qian, N Al-Chalabi… - Psychiatry …, 2021 - Elsevier
Schizophrenia (SCZ) is a chronic psychotic disorder that contributes significantly to
disability, affecting behavior, thought, and cognition. It has long been known that there is a …