[HTML][HTML] Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array
Background DNA methylation has been recognized as a key mechanism in cell
differentiation. Various studies have compared tissues to characterize epigenetically …
differentiation. Various studies have compared tissues to characterize epigenetically …
[HTML][HTML] DNA methylome profiling of human tissues identifies global and tissue-specific methylation patterns
Background DNA epigenetic modifications, such as methylation, are important regulators of
tissue differentiation, contributing to processes of both development and cancer. Profiling the …
tissue differentiation, contributing to processes of both development and cancer. Profiling the …
[HTML][HTML] Tissue specific differentially methylated regions (TDMR): Changes in DNA methylation during development
Tissue specific differentially methylated regions (TDMRs) were identified and localized in the
mouse genome using second generation virtual RLGS (vRLGS). Sequenom MassARRAY …
mouse genome using second generation virtual RLGS (vRLGS). Sequenom MassARRAY …
Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue-and individual-specific DNA methylation patterns
HM Byun, KD Siegmund, F Pan… - Human molecular …, 2009 - academic.oup.com
DNA methylation is known to be associated with cell differentiation, aging, disease and
cancer. There exists an expanding base of knowledge regarding tissue-specific DNA …
cancer. There exists an expanding base of knowledge regarding tissue-specific DNA …
Association of tissue-specific differentially methylated regions (TDMs) with differential gene expression
F Song, JF Smith, MT Kimura… - Proceedings of the …, 2005 - National Acad Sciences
Early studies proposed that DNA methylation could have a role in regulating gene
expression during development [Riggs, AD (1975) Cytogenet. Cell Genet. 14, 9–25] …
expression during development [Riggs, AD (1975) Cytogenet. Cell Genet. 14, 9–25] …
An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs)
We report a novel resource (m ethylation p rofiles of D NA, or mPod) for human genome-
wide tissue-specific DNA methylation profiles. mPod consists of three fully integrated parts …
wide tissue-specific DNA methylation profiles. mPod consists of three fully integrated parts …
Comparison of methyl-DNA immunoprecipitation (MeDIP) and methyl-CpG binding domain (MBD) protein capture for genome-wide DNA methylation analysis reveal …
DNA methylation primarily occurs at CpG dinucleotides in mammals and is a common
epigenetic mark that plays a critical role in the regulation of gene expression. Profiling DNA …
epigenetic mark that plays a critical role in the regulation of gene expression. Profiling DNA …
DNA methylation profile of tissue-dependent and differentially methylated regions (T-DMRs) in mouse promoter regions demonstrating tissue-specific gene expression
S Yagi, K Hirabayashi, S Sato, W Li… - Genome …, 2008 - genome.cshlp.org
DNA methylation constitutes an important epigenetic regulation mechanism in many
eukaryotes, although the extent of DNA methylation in the regulation of gene expression in …
eukaryotes, although the extent of DNA methylation in the regulation of gene expression in …
[HTML][HTML] De novo identification of differentially methylated regions in the human genome
Background The identification and characterisation of differentially methylated regions
(DMRs) between phenotypes in the human genome is of prime interest in epigenetics. We …
(DMRs) between phenotypes in the human genome is of prime interest in epigenetics. We …
Methyl-DNA immunoprecipitation (MeDIP): hunting down the DNA methylome
FV Jacinto, E Ballestar, M Esteller - Biotechniques, 2008 - Future Science
One of the most challenging projects in the field of epigenetics is the generation of detailed
functional maps of DNA methylation in different cell and tissue types in normal and disease …
functional maps of DNA methylation in different cell and tissue types in normal and disease …