Chronic lymphocytic leukemia (CLL) is a common leukemia in adults, but its pathogenesis is
still poorly understood. Interleukin-9 (IL-9) is initially described as a growth factor secreted …

Abstract BACKGROUND Interleukin 6 (IL‐6) is a B‐cell growth and differentiation factor,
which may promote the growth of B‐cell neoplasms. In chronic lymphocytic leukemia (CLL) …

The objective of this study was to examine the correlation between serum interleukin-6 (IL-6)
and IL-10 levels and outcome in chronic lymphocytic leukemia (CLL). Serum IL-6 and IL-10 …

We examined the possible role of interleukin 10 (IL-10) in the pathogenesis of human
chronic B-lymphocytic leukemias (B-CLL). With the use of an in vitro culture technique, we …

The tumor microenvironment (TME) is critical to the longevity of tumor B cells in chronic
lymphocytic leukemia (CLL). Bone marrow mesenchymal stem cells (BMMSCs) and the …

Background In this study, we investigated the role and expression of interleukin (IL)− 17A
and IL‐22 in chronic lymphocytic leukemia. Methods We evaluated the expression of …

Chronic lymphocytic leukemia (CLL) is a common leukemia in adults, but its pathogenesis is
still poorly understood. Recently, extensive evidence suggests that the malignant cells of …

Interleukin-21 (IL21) plays an important role in B-cell proliferation, survival and
differentiation. Contrary to its stimulatory effect in normal B cells, it has been shown that it …

The malignant B cells of patients with chronic lymphocytic leukaemia (CLL) constitutively
express interleukin 8 (IL‐8) and IL‐8 receptors. Ex vivo culture with exogenous IL‐8 …

The recently discovered cytokine, interleukin-15 (IL-15), has been demonstrated to share
several biologic properties with IL-2 in different cell systems, including T-cell and natural …